Autor: Yinglian Xiao, Yuwen Li, Jianchang Shu, Yan Li Jianming Xu, Jianlin Ren, Deliang Liu, Jiangbin Wang, Liya Zhou, Yanqing Li, Guodou Tang, De’an Tian, Shutian Zhang, Xiaohua Hou, Huahong Wang, Zhaoshen Li, Nonghua Lv, Minhu Chen Abstract Background and aim: The treatment of patients with functional dyspepsia (FD) remains unsatisfactory. We assessed the efficacy of Zhizhu Kuanzhong (ZZKZ) capsule, a traditional Chinese medicine formula, in patients with postprandial distress syndrome (PDS) of FD.  Methods: The study was designed as a multicenter, randomized, double-blinded, controlled clinical trial. Three-hundred ninety-two patients with PDS defined by Rome III criteria from 16 centers in China were...Weiterlesen

Abstract BackgroundBased on 122 cases reported in China, data mining indicated that Sini Powder (SNP) and the Zuojin Pill (ZJP) are both widely used as the basic recipe for treating Gastroesophageal Reflux Disease (GERD). ObjectivesTo evaluate the intervention effects of Sini Zuojin Decoction (SNZJD) in patients with GERD. MethodsA comprehensive collection of randomized controlled trials (RCTs) using SNZJD in patients with GERD that were published in domestic and foreign journals was made by computer retrieval. RevMan 5.3 software was used for meta-analysis and bias risk assessment, Stata 14.0 software was used for sensitivity analysis, GRADE profiler 3.6 was used to...Weiterlesen

Abstract Background Acupuncture has been used for chronic constipation, but evidence for its effectiveness remains scarce. Objective To determine the efficacy of electroacupuncture (EA) for chronic severe functional constipation (CSFC). Design Randomized, parallel, sham-controlled trial. (ClinicalTrials.gov: NCT01726504). Setting 15 hospitals in China. Participants Patients with CSFC and no serious underlying pathologic cause for constipation. Intervention 28 sessions of EA at traditional acupoints or sham EA (SA) at nonacupoints over 8 weeks. Measurements The primary outcome was the change from baseline in mean weekly complete spontaneous bowel movements (CSBMs) during weeks 1 to 8. Participants were followed until week 20. Results...Weiterlesen

Abstract Objective To optimize preliminarily acupuncture regimen for gastroesophageal reflux disease (GERD). Methods A total of 80 patients of GERD were taken as the subjects in observation. The reflux disease questionnaire (RDQ) was adopted to assess the relevant indicators. The orthogonal design method was used to observe the effects on GERD in acupuncture regimen with difference combinations among 5 factors and 2 levels at Nèiguān (内关PC 6), including reinforcing-reducing technique by rotating needle (A), time of rotating needle (B), supplementary acupoint (C), time of needle retention (D) and treatment interval (E). The primary and secondary functions among 5 factors (variance...Weiterlesen

Abstract BACKGROUND & AIMS: The Chinese herbal medicine, MaZiRenWan (MZRW), has been used for more than 2000 years to treat constipation, but it has not been tested in a randomized controlled trial. We performed a trial to evaluate the efficacy and safety of MZRW, compared with the stimulant laxative senna or placebo, for patients with functional constipation (FC). METHODS: We performed a double-blind, double-dummy, trial of 291 patients with FC based on Rome III criteria, seen at 8 clinics in Hong Kong from June 2013 through August 2015. Patients were observed for 2 weeks and then assigned randomly (1:1:1) to...Weiterlesen

Abstract BACKGROUND: The main symptoms of gastroesophageal reflux disease GERD are heartburn and acid regurgitation. Proton-pump inhibitors (PPI) are considered to be safe and effective for the treatment of GERD. In traditional Chinese medicine, wu chu yu tang (WCYT) is used to treat nausea after eating, vomiting, and diarrhea. PURPOSE: We designed a randomized, double-blind, placebo-controlled clinical trial to evaluate the therapeutic effect of WCYT on GERD using omeprazole as a PPI for the positive control. METHODS: Ninety patients with GERD were randomly assigned to the 1) control group (CG), who received an oral administration of omeprazole (20 mg) once per...Weiterlesen

Acupuncture ranks as one of the best non-pharmacological treatments for functional chronic constipation (CFC), according to a network meta-analysis carried out by Chinese authors. They included 33 randomised trials with 4324 participants, which compared eight non-pharmacological treatments with placebo, sham interventions, or conventional treatment. Compared with placebo interventions, TENS, probiotics and acupuncture had a significantly larger effect on stool frequency. Patients treated with acupuncture also showed significantly higher rates of response to treatment, while moxibustion had a significantly larger effect on Bristol stool scores. Compared with laxatives, acupuncture had a significantly larger effect on stool frequency, with a lower rate...Weiterlesen

Chinese investigators have concluded that acupuncture can be an effective treatment for obesity, based on a systematic review of 21 studies with 1389 participants. When compared with sham acupuncture, significant reductions in BMI, weight, body fat mass and total cholesterol were found. When compared with no treatment, they found significant reductions of BMI, waist-to-hip ratio, total cholesterol and triglycerides were found. When compared with diet and exercise, significant reduction in BMI and weight were found. The authors suggest that neuroendocrine regulation might be involved in acupuncture’s mechanism of action on obesity. Acupuncture on Obesity: Clinical Evidence and Possible Neuroendocrine Mechanisms....Weiterlesen

ABSTRACT Objective To observe the clinical effects on simple obesity treated with the combined therapy of penetration needling, flash-fire cupping method and auricular acupuncture. Methods In 90 patients of simple obesity, the Bo’s abdominal acupuncture therapy was adopted. Taking Shénquè (神阙CV 8), the points 2 cun directly below CV 8 and 2 cun directly above CV 8 as the landmarks, 3 cun bilateral to each of the above three points, and penetrated through to the conception vessel. Then the electroacupuncture apparatus was connected, with the disperse-dense wave for 30 min. After acupuncture, the glass cup of the middle size was used to stimulate the selected points...Weiterlesen

Original Titel: The effect of ginger supplementation on lipid profile: A systematic review and meta-analysis of clinical trials Erhöhte Blutfette stellen einen großen Risikofaktor für die koronare Herzkrankheit dar. Ingwer könnte helfen, diese zu senken, wie die vorliegende Studie zeigte. Hierbei schien jedoch weniger mehr zu sein. Erhöhte Blutfettwerte sind eine Hauptursache für die koronare Herzkrankheit. Diese zu senken ist somit wichtig, um der KHK vorzubeugen. Doch auch bei bereits bestehender Erkrankung ist es wichtig, eventuell zu hohe Blutfette zu senken, um das Risiko für Folgeerkrankungen wie z. B. einen Herzinfarkt zu reduzieren. In der Regel werden hierfür Statine eingesetzt, doch auch Ingwer wird eine blutfettsenkende Wirkung...Weiterlesen