Wirksamkeit von Akupunktur bei chronischer, therapieresistenter Plantarfasziitis: eine randomisierte Studie Abstract Plantar fasciitis (PF) is a leading cause of heel pain, yet effective treatments for chronic, recalcitrant cases are scarce. The aim of this randomized, no-treatment-controlled trial was to assess whether acupuncture (a combination of high- and low-intensity acupuncture) would reduce pain in patients with chronic recalcitrant PF compared to a waitlist control. Participants were randomly assigned (2:1:1) to high-intensity acupuncture (n = 60), low-intensity acupuncture (n = 30), or waitlist control (n = 30). The primary outcome was the proportion of responders (≥50 % reduction in worst pain intensity)...Weiterlesen

Akupunktur bei Herzrhythmusstörungen: eine systematische Übersichtsarbeit und Metaanalyse Abstract Background Arrhythmia is common, and some patients respond poorly or experience adverse reactions to standard cardioversion therapies, highlighting the need for safer adjunctive options. Although acupuncture has shown potential benefits, prior reviews have primarily focused on efficacy, and no systematic evaluation of its safety in arrhythmia has been conducted. To systematically assess the risk of adverse events (AEs) associated with acupuncture in patients with cardiac arrhythmias. Methods A systematic search of PubMed, Web of Science, EMBASE, China National Knowledge Infrastructure, Wanfang, and VIP Database for Chinese Technical Periodicals (VIP) databases was...Weiterlesen

Handgelenk-Knöchel-Akupunktur zur Prophylaxe von postoperativer Übelkeit und Erbrechen bei weiblichen Hochrisikopatientinnen: eine pragmatische, randomisierte, einfach verblindete, scheinkontrollierte Studie Abstract Background Postoperative nausea and vomiting (PONV) affects up to 80% of high-risk patients, compromising Enhanced Recovery After Surgery (ERAS) outcomes and prolonging hospitalization. This randomized controlled trial evaluated wrist-ankle acupuncture (WAA) efficacy for PONV prevention in high-risk female surgical patients. Methods This single-center, randomized, patient- and assessor-blinded, sham-controlled trial enrolled female patients (aged 18-60 years, ASA I-II) scheduled for elective surgery under general anesthesia with documented motion sickness or previous PONV. Participants received either WAA (sterile needles at four standardized acupoints,...Weiterlesen

Akupunktur bei prämaturer Ovarialinsuffizienz: eine systemische neuroendokrine Perspektive Abstract Premature ovarian insufficiency (POI) is increasingly viewed not merely as an ovarian-centered reproductive disorder but as a systemic neuroendocrine condition characterized by multilevel dysregulation spanning the central nervous system, ovaries, immune system, metabolism, and stress-response networks. Beyond disruption of the hypothalamic-pituitary-ovarian (HPO) axis, POI involves impairment of the KNDy-GnRH network, chronic inflammatory activation, gut-ovary axis-related metabolic disturbances, and dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis and autonomic nervous system. Acupuncture has been proposed as a multi-target neuroendocrine intervention whose effects may extend beyond local ovarian regulation toward broader physiological modulation. Available evidence...Weiterlesen

Akupunkturtherapie bei Post-Stroke-Spastik: eine systematische Übersichtsarbeit und explorative Netzwerk-Metaanalyse zu klinischer Wirksamkeit und Dosis-Wirkungs-Beziehung Abstract Background and purpose Acupuncture has shown good therapeutic potential in post-stroke spasticity (PSS). We aimed to evaluate the clinical efficacy and optimal acupuncture type and dose of acupuncture for PSS. Methods A comprehensive literature search was conducted across 8 databases (PubMed, Embase, Web of Science, Cochrane Library, Chinese National Knowledge Infrastructure (CNKI), Chinese Science and Technology Periodical Databases (VIP), Chinese Biomedical Literature database (Sinomed), and Wan Fang database) to search randomized controlled trials (RCTs) of acupuncture for PSS from their inception to December 1, 2025....Weiterlesen

Antitumorale Effekte von Akupunktur und Moxibustion: von Immunmodulation zur Umgestaltung des Tumormikromilieus Abstract Acupuncture and moxibustion are evidence – based modalities derived from traditional Chinese medicine. They employ strategic needle insertion or moxa – derived thermal stimulation at specific acupoints to ameliorate pathological conditions. Robust clinical data have validated their efficacy in mitigating gastrointestinal dysfunction, chemotherapy – induced neuropathy, cancer – related fatigue, and radiation – induced xerostomia. Crucially, within immunosuppressive tumor microenvironments (TME), these interventions exert direct antitumor effects through multimodal immunomodulation (1): Potentiation of innate immunity via enhanced cytotoxicity of natural killer (NK) cells, polarization of macrophages toward the proinflammatory M1...Weiterlesen

Auf dem Weg zur Präzisionsakupunktur bei Schmerz: Genetische Variabilität des Wirts, Omics-Biomarker und Stratifizierung des Therapieansprechens Abstract Pain is a heterogeneous clinical condition characterized by substantial interindividual variability in symptom severity and treatment response. Acupuncture has been widely used for the management of various pain disorders, including chronic musculoskeletal pain, migraine, and cancer-related pain. However, clinical outcomes remain highly variable across patients, suggesting that average treatment effects may not fully capture biologically and clinically meaningful response heterogeneity. Recent advances in human genetics and multiomics technologies have provided new opportunities to investigate the biological factors that may contribute to this variability....Weiterlesen

Die Rolle der Akupunktur als Komplementärtherapie bei Sepsis: eine narrative Übersichtsarbeit zur Evidenzlage und zukünftigen Studienrichtungen Abstract Sepsis is a life-threatening condition caused by a dysregulated host response to infection. Current interventions are insufficient to halt rising morbidity and mortality, prompting interest in complementary therapies including acupuncture. This narrative review systematically searched clinical studies published from 2010 to 2026 evaluating acupuncture as a complementary therapy for sepsis. Seventeen studies met inclusion criteria. We analyzed study design, participant characteristics, intervention modalities, acupoint selection, outcome measures, and safety, and explored connections between traditional Chinese medicine and modern biomedical mechanisms. The available evidence...Weiterlesen

Einfluss von Akupunktur und Moxibustion auf postoperative gastrointestinale Dysfunktion bei Patient:innen mit gastrointestinalen Karzinomen: Eine Netzwerk-Metaanalyse Abstract Objective This study aims to evaluate and compare the relative efficacy and safety of acupuncture and moxibustion interventions for the recovery of gastrointestinal function and the incidence of adverse reactions after gastrointestinal cancer (GIC) surgery. Methods Eight databases were retrieved up to July 2025. The observation indicators included: time to first flatus, defecation, food intake, and bowel sound; incidence of postoperative adverse reactions (nausea and vomiting, abdominal distension and diarrhea, and ileus); and clinical efficacy rate. Risk of bias was assessed using the...Weiterlesen

Akupunktur bei primärer Hypertonie: eine systematische Übersichtsarbeit und Metaanalyse randomisierter kontrollierter Studien Abstract Objective This systematic review and meta-analysis evaluated the efficacy and safety of acupuncture for primary hypertension, based on randomised controlled trials (RCTs) published between 2015 and 2024. Methods We searched seven major databases for RCTs comparing acupuncture to control interventions. The primary outcomes were changes in systolic blood pressure (SBP) and diastolic blood pressure (DBP). Meta-analyses utilised random-effects models, and the Cochrane Risk of Bias tool assessed study quality. Results Seven RCTs (n = 812) were included. Acupuncture was associated with lower SBP [mean differences (MD) = −6.73 mmHg, 95% confidence interval...Weiterlesen