Akupunktur lindert Angst und Depression bei Ratten mit Durchfall-dominantem Reizdarmsyndrom über die Darm-Hirn-Achse   Abstract Anxiety and depression frequently occur in patients with irritable bowel syndrome (IBS), a disordered long-term digestive disease affecting the stomach and intestine. The symptoms include stomach cramps, bloating, diarrhea/constipation, or both. There are four subcategories: irritable bowel syndrome with diarrhea (IBS-D), irritable bowel syndrome with constipation (IBS-C), irritable bowel syndrome with mixed bowel habits (IBS-M), and irritable bowel syndrome undefined subtype (IBS-U). The coexistence of depression with IBS significantly impairs the patient’s quality of life. Although the underlying mechanisms of IBS are still not fully...Weiterlesen

Auswirkungen von Akupunktur und Massage auf Schmerzen bei jugendlichen und jungen erwachsenen Patient*innen mit fortgeschrittenem Krebs: Subgruppenanalyse einer randomisierten klinischen Studie Abstract Purpose Pain management remains challenging for adolescent and young adult (AYA) cancer patients. Acupuncture and massage have been recommended for cancer-related pain management, but no prospective trials have been conducted in AYA patients. We explored the effects of acupuncture and massage on pain in AYAs. Methods This subgroup analysis focused on AYA patients (aged 18–39 years) enrolled in a randomized controlled trial comparing acupuncture and massage for pain management in advanced cancer. Interventions were delivered weekly for 10...Weiterlesen

Neue Erkenntnisse zur Akupunktur beim ischämischen Schlaganfall: Orchestrierung des Neuro-Endokrin-Immun-Netzwerks Abstract Ischemic stroke (IS) is a major public health challenge with high rates of mortality and disability. Its pathophysiology is complex and multifactorial. Although the pathogenesis of IS originates from local cerebral ischemia, it progresses to a systemic disorder involving dysfunction of the neuro-endocrine-immune (NEI) network. Acupuncture, a non-pharmaceutical therapy characterized by holistic regulation, holds considerable potential for correcting multi-system imbalances after IS. Nevertheless, how acupuncture coordinates this multi-system network remains poorly understood. This review synthesizes current evidence on the cellular and molecular mechanisms underlying acupuncture’s regulation of neural signaling,...Weiterlesen

Kombinierte Pudendusnerv-Elektroakupunktur und transkranielle Akupunkturstimulation bei vorzeitiger Ejakulation: eine randomisierte klinische Studie Abstract Background Premature ejaculation (PE) is a common and distressing condition with a multifactorial etiology and limited tolerable long-term treatment options. Current literature suggests that neuromodulatory approaches that simultaneously target peripheral reflex pathways and central regulatory mechanisms may provide additive therapeutic benefits. Methods In this single-center, block-randomized clinical study, 120 men with PE were assigned to an observation group (n = 60) or a control group (n = 60). The observation group received pudendal nerve electroacupuncture (PNEA) combined with repetitive transcranial acupuncture stimulation (rTAS) twice weekly for 8...Weiterlesen

Pharmakologische Einblicke in die Traditionelle Chinesische Medizin bei Herzinsuffizienz: Fokus auf kardialen Energiestoffwechsel und Mitochondrienfunktion Abstract Introduction Heart failure (HF) remains a major contributor to global cardiovascular mortality, largely due to disturbances in myocardial energy balance and mitochondrial impairment. Conventional therapies alleviate symptoms and slow disease progression but seldom restore normal cardiac bioenergetics. Traditional Chinese Medicine (TCM) provides a holistic, multitarget therapeutic framework that can influence metabolic and signaling networks involved in maintaining cardiac energy homeostasis. Methods Following the PRISMA framework, a systematic search was carried out for publications from 2021 to 2025 examining TCM-derived compounds or formulations with regulatory...Weiterlesen

Kann Elektroakupunktur die Nachsorge nach einem Schwangerschaftsabbruch wirksam verbessern? Eine systematische Übersicht und Metaanalyse Abstract Objectives This study aims to systematically analyze the effects of acupuncture as an adjunctive therapy for minimizing side effects following miscarriage, particularly focusing on pain relief and physical and emotional stability. By reviewing randomized controlled trials, the study seeks to identify effective acupuncture points and standardize their use in post-abortion care. Methods This study systematically reviewed and analyzed randomized controlled trials on the effectiveness of electroacupuncture in managing pain after miscarriage. The review followed PRISMA guidelines, included eight databases, and focused on comparing electroacupuncture to...Weiterlesen

Wirkung der Akupunktur bei Poor Ovarian Response: eine multizentrische randomisierte kontrollierte Studie Abstract Introduction Acupuncture has been explored as a potential intervention for POR; however, high-quality evidence is limited. This multicenter randomized trial evaluated the effect of acupuncture on the number of oocytes retrieved following controlled ovarian hyperstimulation (COH) in women with POR. Methods This multicenter, randomized, controlled study was conducted at nine tertiary hospitals in China between August 2018 and March 2023, with follow-up extended through March 2024. A total of 140 women aged ≤ 40 years, who met the Bologna criteria and were eligible for the antagonist ovulation...Weiterlesen

Klinische Wirkung und Einflussfaktoren der Akupunktur bei motorischen Funktionsstörungen der Extremitäten nach ischämischem Schlaganfall: Eine systematische Übersicht und explorative Netzwerk-Metaanalyse Abstract Objective This study aimed to evaluate the clinical efficacy of acupuncture in the treatment of limb motor dysfunction following ischemic stroke, and to assess the influence of acupuncture intervention type and treatment dosage on therapeutic outcomes. Methods We conducted comprehensive searches multiple databases (e.g., PubMed, Embase, Cochrane, CNKI) and clinical trial registries for studies published up to 10 December 2024. Limb motor function, assessed using the Fugl-Meyer Assessment, was evaluated as the primary outcome. Data analysis was performed using...Weiterlesen

Akupunktur bei Migräne ohne Aura und konnektivitätsbasierte Wirksamkeitsvorhersage: Eine randomisierte klinische Studie Abstract Importance Connectome-based predictive modeling (CPM) uses a data-driven whole-brain framework to identify connectivity patterns predicting clinical outcomes. However, CPM’s application to acupuncture in migraine without aura (MWOA) remains novel. Objective To evaluate the clinical efficacy of real acupuncture and sham acupuncture in MWOA, and to identify acupuncture-response brain connectivity patterns using CPM analysis of baseline functional magnetic resonance imaging (fMRI) data. Design, setting and participants This single-blinded randomized clinical trial was conducted from June 2021 to June 2023 at Beijing Hospital of Traditional Chinese Medicine in China....Weiterlesen

Akupunktur zur Behandlung therapiebedingter Fatigue bei Krebserkrankungen: Eine kritische systematische Übersicht mit Fokus auf die methodische Bewertung der Verblindung Abstract Background Acupuncture is a method of traditional Chinese medicine that has been adapted in the Western world. The objective of this study was to critically assess the evidence presented in randomized controlled trials (RCTs) about the effectiveness of acupuncture on fatigue in cancer patients. Method: In April 2024 a systematic search was conducted searching five electronic databases to find studies concerning the use, effectiveness and potential harm of acupuncture therapy on cancer patients. Results: From all (1599) search results, 15...Weiterlesen