Neuroplastische Mechanismen der Akupunktur bei der motorischen Erholung nach Schlaganfall: Eine randomisierte Multimodal-MRT-Studie Abstract Background Hemiplegia is a common motor impairment following ischemic stroke. Post-stroke recovery involves extensive reorganization of structural and functional brain networks, which correlates with clinical deficits and recovery. While acupuncture has demonstrated safety and efficacy in improving motor function, robust neuroimaging evidence elucidating its central mechanisms remains limited. This study aimed to investigate the specific neuroplastic effects of acupuncture by focusing on its modulation of cortical gray matter volume (GMV) and multilayer dynamic functional network topology. Methods Patients with stroke were randomly allocated in a 2:1...Weiterlesen

Therapeutische Wirkmechanismen der Akupunktur bei akuten Schmerzen in der Notaufnahme Abstract Acupuncture has been used for millennia to treat pain and in recent decades included as an evidence-based strategy for comprehensive pain care. More recently, acupuncture has also been used to treat acute peri‑operative pain and acute pain in the Emergency department (ED). While there are models of acupuncture’s effect on chronic pain, the lack of application of those models for acute pain represents a gap in our scientific understanding. Acupuncture in the ED is a single-session dose intervention. In the context of clarifying significant details of an acupuncture intervention...Weiterlesen

Aktueller Stand und zukünftige Perspektiven der Akupunktur bei Insomnie: Von zentralen Mechanismen zu peripheren Effekten Abstract Insomnia significantly impacts mental health and is linked to a range of other health issues, including cardiovascular diseases, depression and anxiety. Acupuncture, a traditional non-pharmacological intervention, enhances sleep quality by modulating neural circuits and neurotransmitter systems within the brain, particularly in regions such as the hypothalamus, brainstem, and limbic system. It can regulate circadian rhythms, facilitate the equilibrium of neurohormones and neurotransmitters, including melatonin, 5-hydroxytryptamine and γ-aminobutyric acid, and mitigate stress responses through the modulation of the hypothalamic-pituitary-adrenal axis. Acupuncture has demonstrated efficacy in...Weiterlesen

Die Rolle der Akupunktur bei Hyperhidrose und vasomotorischem Schwitzen: Evidenz, Mechanismen und Forschungslücken Abstract Background and purpose Hyperhidrosis and thermoregulatory disorders, including menopausal and treatment-induced hot flushes, can significantly impair quality of life. While acupuncture has been proposed as a potential non-pharmacological treatment for these conditions, the quality and consistency of available evidence remain unclear. This review aims to critically assess the current literature on acupuncture for various kinds of hyperhidrosis, evaluating its clinical efficacy, mechanisms of action, and limitations. Methods A narrative review was conducted based on English-language, PubMed-indexed published clinical studies, randomised controlled trials (RCTs), and meta-analyses investigating...Weiterlesen

Akupunktur lindert Angst und Depression bei Ratten mit Durchfall-dominantem Reizdarmsyndrom über die Darm-Hirn-Achse   Abstract Anxiety and depression frequently occur in patients with irritable bowel syndrome (IBS), a disordered long-term digestive disease affecting the stomach and intestine. The symptoms include stomach cramps, bloating, diarrhea/constipation, or both. There are four subcategories: irritable bowel syndrome with diarrhea (IBS-D), irritable bowel syndrome with constipation (IBS-C), irritable bowel syndrome with mixed bowel habits (IBS-M), and irritable bowel syndrome undefined subtype (IBS-U). The coexistence of depression with IBS significantly impairs the patient’s quality of life. Although the underlying mechanisms of IBS are still not fully...Weiterlesen

Auswirkungen von Akupunktur und Massage auf Schmerzen bei jugendlichen und jungen erwachsenen Patient*innen mit fortgeschrittenem Krebs: Subgruppenanalyse einer randomisierten klinischen Studie Abstract Purpose Pain management remains challenging for adolescent and young adult (AYA) cancer patients. Acupuncture and massage have been recommended for cancer-related pain management, but no prospective trials have been conducted in AYA patients. We explored the effects of acupuncture and massage on pain in AYAs. Methods This subgroup analysis focused on AYA patients (aged 18–39 years) enrolled in a randomized controlled trial comparing acupuncture and massage for pain management in advanced cancer. Interventions were delivered weekly for 10...Weiterlesen

Neue Erkenntnisse zur Akupunktur beim ischämischen Schlaganfall: Orchestrierung des Neuro-Endokrin-Immun-Netzwerks Abstract Ischemic stroke (IS) is a major public health challenge with high rates of mortality and disability. Its pathophysiology is complex and multifactorial. Although the pathogenesis of IS originates from local cerebral ischemia, it progresses to a systemic disorder involving dysfunction of the neuro-endocrine-immune (NEI) network. Acupuncture, a non-pharmaceutical therapy characterized by holistic regulation, holds considerable potential for correcting multi-system imbalances after IS. Nevertheless, how acupuncture coordinates this multi-system network remains poorly understood. This review synthesizes current evidence on the cellular and molecular mechanisms underlying acupuncture’s regulation of neural signaling,...Weiterlesen

Kombinierte Pudendusnerv-Elektroakupunktur und transkranielle Akupunkturstimulation bei vorzeitiger Ejakulation: eine randomisierte klinische Studie Abstract Background Premature ejaculation (PE) is a common and distressing condition with a multifactorial etiology and limited tolerable long-term treatment options. Current literature suggests that neuromodulatory approaches that simultaneously target peripheral reflex pathways and central regulatory mechanisms may provide additive therapeutic benefits. Methods In this single-center, block-randomized clinical study, 120 men with PE were assigned to an observation group (n = 60) or a control group (n = 60). The observation group received pudendal nerve electroacupuncture (PNEA) combined with repetitive transcranial acupuncture stimulation (rTAS) twice weekly for 8...Weiterlesen

Pharmakologische Einblicke in die Traditionelle Chinesische Medizin bei Herzinsuffizienz: Fokus auf kardialen Energiestoffwechsel und Mitochondrienfunktion Abstract Introduction Heart failure (HF) remains a major contributor to global cardiovascular mortality, largely due to disturbances in myocardial energy balance and mitochondrial impairment. Conventional therapies alleviate symptoms and slow disease progression but seldom restore normal cardiac bioenergetics. Traditional Chinese Medicine (TCM) provides a holistic, multitarget therapeutic framework that can influence metabolic and signaling networks involved in maintaining cardiac energy homeostasis. Methods Following the PRISMA framework, a systematic search was carried out for publications from 2021 to 2025 examining TCM-derived compounds or formulations with regulatory...Weiterlesen

Kann Elektroakupunktur die Nachsorge nach einem Schwangerschaftsabbruch wirksam verbessern? Eine systematische Übersicht und Metaanalyse Abstract Objectives This study aims to systematically analyze the effects of acupuncture as an adjunctive therapy for minimizing side effects following miscarriage, particularly focusing on pain relief and physical and emotional stability. By reviewing randomized controlled trials, the study seeks to identify effective acupuncture points and standardize their use in post-abortion care. Methods This study systematically reviewed and analyzed randomized controlled trials on the effectiveness of electroacupuncture in managing pain after miscarriage. The review followed PRISMA guidelines, included eight databases, and focused on comparing electroacupuncture to...Weiterlesen