Intradermale Akupunktur bei mittelschwerer bis schwerer Trockenheit der Augen: eine randomisierte kontrollierte Pilotstudie Abstract Objectives The aim of this study was to evaluate the efficacy of intradermal acupuncture for the treatment of moderate to severe dry eye disease (DED). Methods Thirty patients with moderate to severe DED were randomly assigned (11) to either the Intradermal Acupuncture Group (IAG) or the Body Acupuncture Group (BAG). Both groups received 12 treatment sessions over four weeks (three times per week). The primary outcome was the Ocular Surface Disease Index (OSDI). Secondary outcomes included the Visual Analog Scale (VAS) for subjective symptoms, quality of...Weiterlesen

Auswirkungen der Akupunktur auf muskuloskelettale Schmerzen: eine Evidenzkarte Abstract Background Musculoskeletal pain is a leading cause of disability and reduced quality of life worldwide. Given the growing interest in complementary and alternative therapies, acupuncture has been widely explored as a potential treatment for alleviating musculoskeletal pain. This evidence map aimed to identify, describe, and summarize the current available evidence about acupuncture interventions on musculoskeletal pain. Methods For this map, searches were conducted in PubMed, Embase, Cochrane Library, Allied and Complementary Medicine Database (AMED), Web of Science, and Epistemonikos to identify systematic reviews (SRs) with meta-analysis published up to 23 August...Weiterlesen

Untersuchung der zentralen Nervenbahnen, die das Gehirn und periphere Akupunkturpunkte verbinden, unter Verwendung von Nervenmarkern Abstract Background Acupuncture is widely used for therapeutic purposes, but the neural mechanisms underlying its effects are not fully understood. This study aims to investigate the neural projections from acupoints and subcutaneous (sham acupoints) sites to the central nervous system, using retrograde tracing technology, to clarify the specificity of acupuncture’s neural pathways. Methods Adult C57BL/6J mice were injected with the retrograde tracer PRV-CAG-3 × mScarlet at seven acupoints (LI4, GV20, LI11, BL23, LR3, ST25, ST36) and their corresponding subcutaneous sites (sham acupoints). After 120 h, the brains were...Weiterlesen

Immunmodulatorische Wirkungen der Akupunktur auf Makrophagen bei allergischen Erkrankungen: Eine systematische Übersicht Abstract The incidence of allergic diseases has been increasing annually, severely affecting the quality of life of patients. With the growing recognition of traditional medicine, acupuncture, an ancient Chinese therapeutic method, has gradually gained attention for its potential in immune modulation. Studies have shown that macrophages play a crucial role in the development of allergic diseases, and acupuncture may influence allergic reactions by modulating the function of macrophages. This article aims to systematically evaluate the regulatory effects of acupuncture on macrophages in allergic diseases and the corresponding mechanisms....Weiterlesen

Wirksamkeit von Akupunktur im Vergleich zu Sham-Akupunktur bei generalisierten Angststörungen: eine Meta-Analyse randomisierter kontrollierter Studien Abstract Objective This meta-analysis aimed to evaluate the specific efficacy of acupuncture compared to sham acupuncture in the treatment of generalized anxiety disorder (GAD), beyond nonspecific or placebo effects. Methods We systematically searched PubMed, Web of Science, CNKI, WanFang, VIP, Cochrane Library, ClinicalTrials.gov, and EMBASE from inception to October 2025. Randomized controlled trials (RCTs) comparing acupuncture with sham acupuncture in adults diagnosed with GAD were included. Primary outcome was the Hamilton Anxiety Scale (HAMA), with secondary outcomes including Self-Rating Anxiety Scale (SAS), Generalized Anxiety Disorder...Weiterlesen

Neuronale Korrelate der Akupunktur bei vaskulärer kognitiver Beeinträchtigung: Erkenntnisse aus der Ruhezustands-fMRT Abstract Vascular cognitive impairment (VCI) represents a spectrum of cognitive deficits caused by cerebrovascular pathology, affecting multiple cognitive domains including memory, executive function, and attention. While pharmacological interventions for VCI remain limited, growing evidence supports acupuncture as an effective and safe therapeutic approach that improves both global cognition and activities of daily living in affected patients. Nevertheless, the neurobiological mechanisms underlying acupuncture’s therapeutic effects require further elucidation. Resting-state functional magnetic resonance imaging (rs-fMRI) has emerged as a powerful neuroimaging tool for investigating brain function in cognitive disorders. This...Weiterlesen

Akupunktur verbessert funktionelle Einschränkungen bei Krebspatient*innen mit chronischen Schmerzen: Eine Sekundäranalyse der randomisierten klinischen Studie PEACE Abstract This study investigated the effects of electro-acupuncture and auricular acupuncture on pain-related functional impairment in cancer patients with chronic musculoskeletal pain. As a secondary analysis of a randomized clinical trial, participants received acupuncture or were placed on a waitlist control. Functional outcomes for upper and lower limbs were measured using standardized scales. Both forms of acupuncture improved functional performance compared with the control group, with benefits varying over time between upper and lower extremities. Additionally, patients who experienced pain relief showed greater functional...Weiterlesen

Auswirkung der Spezifität von Akupunkturpunkten auf kardiovaskuläre Outcomes: Eine systematische Überprüfung und Meta-Analyse Abstract Background Acupuncture, a cornerstone of Traditional Chinese Medicine (TCM), is increasingly utilized for cardiovascular diseases (CVDs). A central tenet is acupoint specificity – the hypothesis that stimulating specific acupoints yields distinct therapeutic effects compared to non-specific points or sham interventions. However, the empirical evidence supporting acupoint specificity for cardiovascular outcomes remains debated. This systematic review aimed to evaluate the current evidence regarding the impact of acupoint specificity on clinically relevant cardiovascular outcomes. Methods A systematic search was conducted in major biomedical databases (PubMed, Embase, Cochrane Library,...Weiterlesen

Klinische Wirksamkeit der Akupunktur bei der Behandlung von Uteruskontraktionsschmerzen nach einem Kaiserschnitt: Protokoll einer randomisierten, kontrollierten Studie Abstract Purpose Uterine contraction pain post-cesarean section (UCPCS) is one of the main complaints for mothers in the early stages of the puerperium. Acupuncture, a non-pharmacological therapy, has shown sound analgesic effects with almost no toxic side effects. This study uses acupuncture as an intervention and aimed to provide strong evidence for the clinical efficacy of acupuncture in treating UCPCS. Patients and Methods This single-blind, randomized controlled trial (RCT) was conducted at the Ludian County Hospital of Traditional ChineseMedicine, China. Participants (138) are...Weiterlesen

Klinische Wirksamkeit der differenzierenden Meridianakupunktur bei der Behandlung von hartnäckiger Insomnie auf der Grundlage objektiver Daten: Protokoll für eine multizentrische, einfach verblindete, randomisierte kontrollierte Studie   Abstract Introduction Insomnia, a prevalent sleep disorder, significantly impacts individuals‘ physical and mental well-being. Despite conventional treatments, some patients experience persistent insomnia. Acupuncture, a safe complementary therapy, has been demonstrated to be effective in treating insomnia. Meridian differentiation can enhance acupuncture efficacy by enabling individualised diagnosis. Previous clinical research has indicated that meridian differentiation acupuncture (MA), based on objective data, can notably enhance sleep quality in patients with intractable insomnia. However, small sample sizes...Weiterlesen