Antitumorale Effekte von Akupunktur und Moxibustion: von Immunmodulation zur Umgestaltung des Tumormikromilieus Abstract Acupuncture and moxibustion are evidence – based modalities derived from traditional Chinese medicine. They employ strategic needle insertion or moxa – derived thermal stimulation at specific acupoints to ameliorate pathological conditions. Robust clinical data have validated their efficacy in mitigating gastrointestinal dysfunction, chemotherapy – induced neuropathy, cancer – related fatigue, and radiation – induced xerostomia. Crucially, within immunosuppressive tumor microenvironments (TME), these interventions exert direct antitumor effects through multimodal immunomodulation (1): Potentiation of innate immunity via enhanced cytotoxicity of natural killer (NK) cells, polarization of macrophages toward the proinflammatory M1...Weiterlesen

Einfluss von Akupunktur und Moxibustion auf postoperative gastrointestinale Dysfunktion bei Patient:innen mit gastrointestinalen Karzinomen: Eine Netzwerk-Metaanalyse Abstract Objective This study aims to evaluate and compare the relative efficacy and safety of acupuncture and moxibustion interventions for the recovery of gastrointestinal function and the incidence of adverse reactions after gastrointestinal cancer (GIC) surgery. Methods Eight databases were retrieved up to July 2025. The observation indicators included: time to first flatus, defecation, food intake, and bowel sound; incidence of postoperative adverse reactions (nausea and vomiting, abdominal distension and diarrhea, and ileus); and clinical efficacy rate. Risk of bias was assessed using the...Weiterlesen

Auswirkungen von Akupunktur und Massage auf Schmerzen bei jugendlichen und jungen erwachsenen Patient*innen mit fortgeschrittenem Krebs: Subgruppenanalyse einer randomisierten klinischen Studie Abstract Purpose Pain management remains challenging for adolescent and young adult (AYA) cancer patients. Acupuncture and massage have been recommended for cancer-related pain management, but no prospective trials have been conducted in AYA patients. We explored the effects of acupuncture and massage on pain in AYAs. Methods This subgroup analysis focused on AYA patients (aged 18–39 years) enrolled in a randomized controlled trial comparing acupuncture and massage for pain management in advanced cancer. Interventions were delivered weekly for 10...Weiterlesen

Akupunktur zur Behandlung therapiebedingter Fatigue bei Krebserkrankungen: Eine kritische systematische Übersicht mit Fokus auf die methodische Bewertung der Verblindung Abstract Background Acupuncture is a method of traditional Chinese medicine that has been adapted in the Western world. The objective of this study was to critically assess the evidence presented in randomized controlled trials (RCTs) about the effectiveness of acupuncture on fatigue in cancer patients. Method: In April 2024 a systematic search was conducted searching five electronic databases to find studies concerning the use, effectiveness and potential harm of acupuncture therapy on cancer patients. Results: From all (1599) search results, 15...Weiterlesen

Akupunktur verbessert funktionelle Einschränkungen bei Krebspatient*innen mit chronischen Schmerzen: Eine Sekundäranalyse der randomisierten klinischen Studie PEACE Abstract This study investigated the effects of electro-acupuncture and auricular acupuncture on pain-related functional impairment in cancer patients with chronic musculoskeletal pain. As a secondary analysis of a randomized clinical trial, participants received acupuncture or were placed on a waitlist control. Functional outcomes for upper and lower limbs were measured using standardized scales. Both forms of acupuncture improved functional performance compared with the control group, with benefits varying over time between upper and lower extremities. Additionally, patients who experienced pain relief showed greater functional...Weiterlesen

Akupunktur bei chronischen Krebsschmerzen: eine systematische Übersicht und Meta-Analyse   Abstract Introduction Pain is highly prevalent among cancer patients. Cancer pain is classified as chronic cancer pain (MG30.10) and chronic post-cancer treatment pain (MG30.11) in the International Classification of Diseases, 11th Revision (ICD-11). This research aims to ascertain the efficacy and safety of acupuncture in treating chronic cancer pain (MG30.10). Methods Eight Chinese and English databases were systematically searched from their inception to December 31, 2024, to identify randomized controlled trials (RCTs) that examined the efficacy of acupuncture in combination with active treatments versus active treatment alone (identical to the treatment group), no...Weiterlesen

Erforschung des Signalwegs und des damit zusammenhängenden Mechanismus der Intervention der traditionellen chinesischen Medizin bei chronischer Gastritis im Rahmen der „Entzündung-Krebs-Transformation“ Abstract Objective The aim of this study is to uncover the traditional Chinese medicine (TCM) treatments for chronic gastritis and their potential targets and pathways involved in the “inflammation-cancer” conversion in four stages. These findings can provide further support for future research into TCM and its active components. Materials and methods The literature search encompassed PubMed, Web of Science, Google Scholar, CNKI, WanFang, and VIP, employing keywords such as “chronic gastritis”, “gastric cancer”, “traditional Chinese medicine”, “medicinal herb”, “Chinese...Weiterlesen

Abstract Purpose The opioid crisis resulting from its use disorder and overdose poses additional challenges for cancer pain management. The American Society of Clinical Oncology Practice Guideline recommends acupuncture therapy for the management of adult cancer-related pain (CRP), but the effectiveness of transcutaneous electrical acupoint stimulation (TEAS) on CRP remains uncertain. Methods This 5-week prospective randomized clinical trial was conducted at 2 hospitals in China, and participants with CRP receiving chronic opioid therapy were randomized 1:1 into two groups between December 2014 and June 2018. The true TEAS group underwent 15 sessions of TEAS treatments over 3 consecutive weeks, while...Weiterlesen

Abstract Background In this study, the impact of a multimodal integrative oncology pre- and intraoperative intervention on pain and anxiety among patients undergoing gynecological oncology surgery was explored. Methods Study participants were randomized to three groups: Group A received preoperative touch/relaxation techniques, followed by intraoperative acupuncture; Group B received preoperative touch/relaxation only; and a control group (Group C) received standard care. Pain and anxiety were scored before and after surgery using the Measure Yourself Concerns and Wellbeing (MYCAW) and Quality of Recovery (QOR-15) questionnaires, using Part B of the QOR to assess pain, anxiety, and other quality-of-life parameters. Results A...Weiterlesen

Abstract Objective To compare the effectiveness of acupuncture alone or with additional integrative oncology modalities for taxane-induced peripheral neuropathy-related symptoms in patients with gynecological and breast cancer. Methods The study was a prospective evaluation of patients undergoing twice-weekly treatments with either acupuncture alone (single-modality, group A) or with additional manual-movement and mind-body therapies (multimodality, group B), for 6 weeks. Symptom severity was assessed at baseline, 6 weeks, and 9 weeks using the Functional Assessment of Cancer Therapy-Taxane (FACT-Tax) tool; and von Frey perception thresholds. Additional symptoms were also assessed with the European Organization for Research and Treatment of Cancer Quality...Weiterlesen