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Onkologie und Supportive Cancer Care
Original Titel: Efficacy of Acupuncture Therapy for Chemotherapy-Related Cognitive Impairment in Breast Cancer Patients DGP – Chinesische Forscher erprobten in ihrer Studie, ob die Akupunktur geeignet sein könnte, um Beeinträchtigungen der Denkleitung zu vermindern, die Brustkrebspatientinnen, die eine Chemotherapie erhalten, betreffen können. Die kleine Studie zeigte vielversprechende Erfolge der Akupunktur – die Patientinnen, die die Akupunktur erhielten, schnitten in der Folge in zahlreichen Tests zur Messung der Denkleistung besser ab. Durch Chemotherapie kann die Prognose von Brustkrebspatientinnen oftmals deutlich verbessert werden – allerdings können mit der Chemotherapie auch Nebenwirkungen einhergehen, die zahlreiche Organe betreffen können. Manche Krebspatienten entwickeln durch die Chemotherapie Beeinträchtigungen der Denkleistung, sogenannt kognitive Beeinträchtigungen. Chinesische Forscher erproben, ob...
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Abstract Background: A natural-killer (NK) cell is a cytotoxic lymphocyte that responds to tumor formation. Electroacupuncture (EA) in patients with cancer, who had chemotherapy, enabled them to maintain their T-cell counts (CD3+, CD4+, and CD8+) and NK-cell activity. Objective: To evaluate NK-cell levels and tumor sizes in patients with cervical squamous-cell carcinoma (SCC) after EA on ST 36 (Zusanli). Design: This study was a randomized, experimental clinical study with a pre–post-test, control group design. Setting The study was performed in the obstetrics and gynecology department, Gynecology Oncology Division of the Rumah Sakit Dokter Soetomo General Hospital, in Surabaya, Jawa Timur, Indonesia, conducted from...
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Acupuncture can assist recovery following surgery for colorectal cancer (CRC). Chinese researchers included 22 studies (1,628 participants) in their analysis. The results suggested that the addition of acupuncture following CRC surgery improved recovery of gastrointestinal function. Meta-analyses found significant reductions in time to first bowel sounds, first flatus and first defecation, in both the sham-controlled and non-blinded studies. The best evidence was for interventions that included electro-acupuncture at the point Zusanli ST-36. Acupuncture and Related Therapies for Treatment of Postoperative Ileus in Colorectal Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Evid Based Complement Alternat Med. 2018 Jul...
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DGP – Akupunktur konnte bei älteren Brustkrebspatientinnen Gelenkschmerzen mindern, die durch die Behandlung mit Aromatasehemmern hervorgerufen werden. Unklar bleibt, ob die Reduktion der Schmerzen durch die Akupunktur deutlich genug ist. Original Titel: Effect of Acupuncture vs Sham Acupuncture or Waitlist Control on Joint Pain Related to Aromatase Inhibitors Among Women With Early-Stage Breast Cancer: A Randomized Clinical Trial Eine Antihormontherapie mit Aromatasehemmern führt bei Brustkrebspatientinnen häufig zu Gelenkschmerzen, die einen Abbruch der Therapie bedingen können. Ergebnisse von einigen kleineren Studien weisen darauf hin, dass Akupunktur diese Schmerzen verringern könnte. Brustkrebspatientinnen mit Gelenkschmerzen in 11 Forschungszentren untersucht US-amerikanische Forscher führten zu diesem Thema eine Studie durch, die an 11...
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Abstract Objective To observe the clinical therapeutic effects of acupuncture on chemotherapy-induced hand-foot syndrome (HFS). Methods A total of 60 patients treated with chemotherapy of capecitabine and suffering from the chemotherapy-induced HFS were divided into an acupuncture group and a Vitamin B6 group according to the random number table, 30 cases in each one. In the acupuncture group, after chemotherapy, acupuncture was given at Băihuì (百会GV 20), Hégŭ (合谷LI 4), Wàiguān (外关TE 5), Zúsānlĭ (足三里ST 36) and Ashi points. The needles were retained for 30 min in each treatment, once a day, totally for 2 weeks. In the Vitamin B6 group, after chemotherapy, Vitamin B6 was taken orally, 300 mg a day, totally for 2 weeks....
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Original Titel: Acupuncture is shown to relieve symptoms of joint pain from aromatase inhibitor treatment. DGP – Akupunktur erwies sich in dieser Studie als hilfreich, um Gelenkschmerzen zu mildern, die Brustkrebspatientinnen unter einer Hormontherapie belasten. Die Behandlung von Patientinnen mit Hormonrezeptor-positivem Brustkrebs erfolgt meistens mit hormoneller Therapie. Da diese Brusttumore in Abhängigkeit von den weiblichen Geschlechtshormonen, wie z. B. Estrogen wachsen, kann ein Hormonentzug dem Krankheitsfortgang entgegenwirken. Die sogenannten Aromatasehemmer sind Substanzen, welche die Bildung der weiblichen Geschlechtshormone hemmen und somit das Tumorwachstum bremsen können. Die Behandlungsdauer beträgt bei Patientinnen in der Menopause zwischen 5 und 7 Jahren, wird aber oftmals aufgrund der damit einhergehenden Gelenkschmerzen abgebrochen. Ist Akupuntkur...
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Abstract BACKGROUND: Bortezomib-induced peripheral neuropathy (BIPN) is a common and debilitating side effect. Our pilot study demonstrated that acupuncture is safe and can decrease total neuropathic symptoms. However, there is lack of knowledge in which individual BIPN symptoms benefited from acupuncture. PURPOSE: To characterize individual symptoms reduced by acupuncture in patients with BIPN. METHODS: Patients with multiple myelomatreated with bortezomib who developed BIPN grade 2 or above, based on National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE), were enrolled and received 10 acupuncture treatments over 10 weeks. Self-reported BIPN-associated symptoms assessments were collected weekly at baseline, during,...
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Key Points Question Does acupuncture reduce joint pain related to aromatase inhibitors among postmenopausal women with early-stage breast cancer? Findings In this multicenter randomized clinical trial of 226 women with early-stage breast cancer, patients in the acupuncture group, compared with those in the sham acupuncture group or the waitlist control group, had significant reductions in changes in joint pain scores from baseline to 6 weeks (between-group difference vs sham acupuncture, 0.92 points and 0.96 points vs the waitlist control group [0- to 10-point scale]). Meaning Acupuncture was associated with statistically significant reductions in aromatase inhibitor–related joint pain at 6 weeks,...
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Abstract OBJECTIVE To observe the effect of compound Zhebei granules (CZBG) with chemotherapy in the treatment of refractory acute leukemia. METHODS In this multicenter, double-blind, placebo-controlled clinical trial, we used a central (online) randomization system to assign 235 patients to two treatment groups. A total of 118 patients received chemotherapy combined with CZBG (4 g, twice daily) and 117 patients received chemotherapy plus placebo. The clinical efficacy was evaluated at the end of one chemotherapeutic cycle. RESULTS In the full analysis set, in which deaths due to disease progression were regarded as inefficacy, the rates of complete remission (CR) and partial remission (CR+PR) were 32.35%...
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In a collaborative study between Chinese and US cancer centres, the Chinese formula Ren Shen Yang Rong Tang (RSYRT, ‘Ginseng Decoction to Nourish the Nutritive Qi’) has been found to significantly reduce severe fatigue in cancer patients. RSYRT is a tonic formula containing 12 herbs: Bai Shao (Radix Paeoniae alba, Dang Gui Radix (Angelicae Sinensis) Chen Pi (Pericarpium Citri Reticulatae), Huang Qi (Radix Astragali), Rou Gui (Cortex Cinnamomi Cassiae), Ren Shen (Radix Ginseng), Bai Zhu (Rhizoma Atractylodis Macrocephalae, Gan Cao (Radix Glycyrrhizae), Shu Di Huang (Radix Rehmanniae Glutinosae Praeparata, Wu Wei Zi (Fructus Schisandrae Chinensis), Fu Ling (Sclerotium Poriae Cocos),...
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