Autor: Junying Zhang, Caishui Yang, Dongfeng Wei, He Li, Elaine Lai-Han Leung, Qingqiong Deng, Zhen Liu, Xing-Xing Fan, Zhanjun Zhang Abstract Mild cognitive impairment (MCI), regarded as the prodromal stage before the clinical phase of Alzheimer’s disease (AD), has been considered for early intervention. Unfortunately, many trials in this stage with drugs with single-target turned out to be little or no effect. Multi-targeting in nature based...Weiterlesen

Autor: Anna Benrick, Nicolas J Pillon, Emma Nilsson, Eva Lindgren, Anna Krook, Charlotte Ling, Elisabet Stener-Victorin Abstract Context: Autonomic nervous system activation mediates the increase in whole-body glucose uptake in response to electroacupuncture but the mechanisms are largely unknown.  Objective: To identify the molecular mechanisms underlying electroacupuncture-induced glucose uptake in skeletal muscle in insulin-resistant overweight/obese women with and without polycystic ovary syndrome (PCOS).  Design/participants: In a case-control study, skeletal...Weiterlesen

Autor: Hong Ping Zhang, Lei Wang, Zhen Wang, Xian Rong Xu, Xian Mei Zhou, Gang Liu, Lv Yuan He, Jun Wang, Alan Hsu, Wei Min Li, Gang Wang Abstract Background: Despite advances in asthma management, exacerbations constitute a significant health economic burden.  Objective: To observe the efficacy and safety of Chinese herbal medicine formula entitled PingchuanYiqi (PCYQ) granule, on acute asthma and to explore its possible mechanism.  Materials...Weiterlesen

Autor: Zongshi Qin, Yulong Ding, Chang Xu, Joey S W Kwong, Yuan Ji, Aimin Wu, Jiani Wu, Zhishun Liu Abstract Background: Acupuncture is commonly used to treat degenerative lumbar spinal stenosis in Asian countries. However, rigorous data regarding the efficacy and safety of acupuncture for aging patients are currently lacking.  Methods: Eighty patients older than 50 years were assigned randomly to the acupuncture group or the noninsertive sham...Weiterlesen

Autor: Juan Li, Wanting Wu, Elisabet Stener-Victorin, Ernest Hung Yu Ng, Raymond Hang Wun Li, Meifang Li, Hua Liu, Maohua Lai, Yanbing Meng, Yanhua Zheng, Yang Xia, Hongxia Ma Abstract Objective: To test the hypothesis that acupuncture improves insulin sensitivity in women with polycystic ovary syndrome (PCOS) and insulin resistance (IR).  Design: Prospective pilot study.  Setting: Guangzhou, China, 2014-2016.  Participants: Eighty women with PCOS aged 18-40 years with body mass...Weiterlesen

Abstract ETHNOPHARMACOLOGICAL RELEVANCEFufang Chuanxiong capsule consists of Angelica sinensis radix and Chuanxiong rhizome, which are used in the traditional Chinese medicine for the treatment of coronary artery disease, and Xinyue capsule is composed of panax quinquefolius saponin extracted from leaves and stems of Panax quinquefolium L, which has the functions of anti-myocardial ischemia, improving myocardial energy metabolism and inhibiting apoptosis of cardiomyocytes. OBJECTIVETo observe the...Weiterlesen

Abstract Subcutaneous mast cells (MCs) are vulnerable to mechanical stimulation from external environment. Thus, MCs immune function could be modulated by their mechanosensitivity. This property has been identified as the trigger mechanism of needling acupuncture, a traditional oriental therapy. Previously we have demonstrated the release of adenosine triphosphate (ATP), a stress-responsive signalling molecule, from mechanical-perturbed MCs. The current work explores its underlying mechanisms. We noticed...Weiterlesen

Abstract ETHNOPHARMACOLOGICAL RELEVANCEWith the extensive recent use of warfarin and traditional Chinese medicine (TCM) in combination, TCM has been found to affect warfarin’s pharmacokinetic and pharmacodynamic parameters. Warfarin is a widely used oral anticoagulant, which has a narrow therapeutic window and a high likelihood of interacting with other drugs and resulting in serious adverse reactions. Contrary to widespread public expectations, TCM, despite being natural, is...Weiterlesen

Abstract BackgroundBased on 122 cases reported in China, data mining indicated that Sini Powder (SNP) and the Zuojin Pill (ZJP) are both widely used as the basic recipe for treating Gastroesophageal Reflux Disease (GERD). ObjectivesTo evaluate the intervention effects of Sini Zuojin Decoction (SNZJD) in patients with GERD. MethodsA comprehensive collection of randomized controlled trials (RCTs) using SNZJD in patients with GERD that were published...Weiterlesen

BackgroundTraditional Chinese Medicine (TCM) has gradually drawn the attention of clinicians as an alternative choice for insomniacs and TCM Yangxin Anshen Therapy (TYAT) is a crucial therapy of treating insomniacs. The purpose of this study was to evaluate the efficacy and safety of TYAT for insomnia.  MethodsSeven electronic databases were searched from inception to July 2019. Two authors independently identified Randomized Controlled Trials (RCTs), extracted...Weiterlesen