Autor: Junying Zhang, Caishui Yang, Dongfeng Wei, He Li, Elaine Lai-Han Leung, Qingqiong Deng, Zhen Liu, Xing-Xing Fan, Zhanjun Zhang Abstract Mild cognitive impairment (MCI), regarded as the prodromal stage before the clinical phase of Alzheimer’s disease (AD), has been considered for early intervention. Unfortunately, many trials in this stage with drugs with single-target turned out to be little or no effect. Multi-targeting in nature based on the theory of Traditional Chinese Medicine (TCM) offers another prospect for intervention. Together with advanced functional magnetic resonance imaging (fMRI) technique for more sensitive and objective evaluation, we investigated the long-term therapeutic effects of...Weiterlesen

Abstract Background Propranolol is recommended as first-line treatment for preventing migraine attacks; acupuncture has not been compared with propranolol in a head-to-head trial. Objective To compare acupuncture with propranolol using indirect treatment comparison meta-analysis. Method We searched MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials (CENTRAL). Randomized controlled trials comparing acupuncture or propranolol with sham acupuncture, placebo, waiting-list control or usual care were included. We extracted information from the included trials using a standardized extraction form. The primary outcome was migraine episodes. The secondary outcomes included migraine days, migraine frequency, and adverse events. Results We included 19 RCTs (n =...Weiterlesen

Abstract OBJECTIVE: To examine the effect of Gua Sha therapy in the treatment of diabetic peripheral neuropathy (DNP). DESIGN: An open-label randomized controlled study was conducted with usual care as the control (60 subjects in Gua Sha group and 59 subjects in usual care group). Outcome measures included Toronto Clinical Scoring System (TCSS), Vibration Perception Threshold (VPT), Ankle Brachial Index (ABI), and fasting plasma glucose (FPG). There were 12 consecutive sessions of Gua Sha, one session per week. RESULTS: After the first cycle of Gua Sha intervention, only performance of sensory function measured by the VPT, and peripheral artery disease...Weiterlesen

Abstract OBJECTIVE: To explore the acupoint selection rules of acupuncture for Alzheimer’s disease (AD) in modern clinical practice by complex network technology. METHODS: The relevant articles of clinical trials were retrieved from CNKI published before December 2017. Using Microsoft Excel 2010, the database was established. Using Gephi 0.8.2 software, the complex network mode was built and its topological structure was analyzed. RESULTS: Finally, 81 articles were eligible and 114 acupoint prescriptions were extracted. The constructed complex network of acupoint prescriptions for AD was characteristics as small world effect and scale-free property, the crucial acupoints included Baihui (GV 20), Sishencong (EX-HN...Weiterlesen

A systematic review and meta-analysis of RCTs Background Bell’s palsy or idiopathic facial paralysis is an acute facial paralysis caused by the inflammation of facial nerve. Several previous studies showed that acupuncture was beneficial in the treatment of facial paralysis. However, its effectiveness is still controversial compared with drug therapy. Therefore, this systematic review and meta-analysis was performed to assess the efficacy of acupuncture for Bell’s palsy. Methods This is a systematic review and meta-analysis of clinical studies among patients with Bell’s palsy. We did a systematic literature search in PubMed, Embase, and the Cochrane Register of Controlled Trials to identify studies comparing the efficacy of acupuncture and drug treatment in treating facial paralysis. The search was last updated on July...Weiterlesen

Abstract PURPOSE: Chemotherapy-induced peripheral neuropathy is a complex side effect with few available treatment options. The aim of the study was to test the effectiveness of an 8-week course of acupuncture in the management of chemotherapy-induced peripheral neuropathy in cancer patients who were receiving or had received neurotoxic chemotherapy. METHODS: Randomized assessor-blinded controlled trial with 2 arms; one arm received acupuncture twice weekly for 8 weeks, while the other arm was a wait-list control group receiving only standard care. Primary outcome was pain intensity and interference over the past week using the Brief Pain Inventory at the end of the...Weiterlesen

Traditional preparation of three herbs relieves and reduces symptoms of disease in mice and tests on humans are encouraging, study finds PUBLISHED: Sunday, 07 December, 2014, 4:47am A traditional Chinese medicine known as smart soup (聰明湯) could help in the fight against Alzheimer’s disease, scientists on the mainland believe. The simple treatment helped relieve and even reverse Alzheimer’s symptoms in mice that had been genetically modified to acquire the disease, researchers with the Chinese Academy of Sciences‘ Institute of Biochemistry and Cell Biology in Shanghai found. The rodents began to show improvements after just six days of being fed the...Weiterlesen

Original Titel: Association of traditional Chinese medicine therapy and the risk of dementia in patients with hypertension: a nationwide population-based cohort study. In früheren Studien wurde ein erhöhten Demenzrisiko von Bluthochdruckpatienten berichtet. Bluthochdruck wird oft mit alternativen Methoden, in Taiwan am häufigsten mit Traditioneller chinesischer Medizin (TCM), behandelt. Bisher ist es jedoch unklar, ob diese Behandlung auch das Demenzrisiko der Patienten senken könnte. Ziel der taiwanesischen Studie von Chen und Kollegen (2017) war es daher, den Effekt von TCM auf das Demenzrisiko bei Bluthochdruckpatienten zu untersuchen. Die Studie rekrutierte 143.382 Patienten aus der Taiwanesischen nationalen Krankenversicherungs-Forschungsdatenbank, bei denen gerade Bluthochdruck...Weiterlesen

Abstract Objective: To observe the clinical efficacy of acupuncture therapy and carbamazepine therapy for primary trigeminal neuralgia. Methods: A total of 150 patients with primary trigeminal neuralgia treated in Department of Rehabilitation Medicine of Linyi Central Hospital from January 2010 to December 2016 were selected. They were divided into acupuncture group (n=75) and drug group (n=75). The patients in the acupuncture group received acupuncture based on the shape of trigeminal nerve once daily with 10 days as a treatment course. The results were observed after two treatment courses. Those in the drug group took 0.1 g carbamazepine three times daily...Weiterlesen

Abstract BACKGROUND: Bortezomib-induced peripheral neuropathy (BIPN) is a common and debilitating side effect. Our pilot study demonstrated that acupuncture is safe and can decrease total neuropathic symptoms. However, there is lack of knowledge in which individual BIPN symptoms benefited from acupuncture. PURPOSE: To characterize individual symptoms reduced by acupuncture in patients with BIPN. METHODS: Patients with multiple myelomatreated with bortezomib who developed BIPN grade 2 or above, based on National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE), were enrolled and received 10 acupuncture treatments over 10 weeks. Self-reported BIPN-associated symptoms assessments were collected weekly at baseline, during,...Weiterlesen