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UK authors have carried out a systematic review of the use of Chinese herbal medicine (CHM) for endometriosis-related pain and infertility. Database searches revealed 100 relevant studies, but only two Chinese RCTs were deemed of high enough quality for analysis. Meta-analysis of the pooled results involving a total of 158 women concluded that administration of CHM after laparoscopic surgery for endometriosis has effects comparable to those achieved with the drug gestrinone (a synthetic progesterone that suppresses the secretion of oestrogen by the ovaries), but with fewer side effects. In addition they concluded that oral CHM may have a better overall treatment effect than danazol (synthetic testosterone) and that it may be more effective in relieving dysmenorrhea and shrinking endometrial masses when used in conjunction with a CHM enema. (Chinese herbal medicine for endometriosis. Cochrane Database Syst Rev. 2009 Jul 8;(3):CD006568)

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