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Studien zum Thema Herz und Kreislauf

Interactions between clopidogrel and traditional Chinese medicine

Abstract The use of traditional Chinese medicine (TCM) has obtained more and more acceptance all over the world due to its multi-target and multi-level function characteristics. Clopidogrel is a major therapeutic option to reduce atherothrombotic events in patients with acute coronary syndrome, recent myocardial infarction, recent stroke or established peripheral arterial disease. These patients probably take TCM. Are there any interactions between clopidogrel and TCM? Whether TCM will affect the efficacy of clopidogrel or increase the adverse reactions of bleeding? Clarifying this information will help physicians make better use of TCM. A literature search was carried out using Web of...
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Transcutaneous Electrical Stimulation of PC5 and PC6 Acupoints Modulates Autonomic Balance in Heart Transplant Patients: A Pilot Study

Abstract The increased resting heart rate (HR) in heart transplant patients is associated with enhanced metabolic demand, the potential for fatigue, and lower quality of life. In the present study, we hypothesized that transcutaneous electrical acupoint stimulation (TEAS) could modulate autonomic balance and reduce resting HR in these patients. A single-arm clinical trial was conducted with patients aged > 18 years, at ambulatorial accompaniment after heart transplantation, who were submitted to a single TEAS (40 minutes at pericardium channel acupoints PC5 and PC6). The arterial blood pressure and RR interval were recorded from 20 minutes before to 20 minutes after...
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Acupuncture as Adjunctive Therapy for Chronic Stable Angina – A Randomized Clinical Trial

Abstract Importance The effects of acupuncture as adjunctive treatment to antianginal therapies for patients with chronic stable angina are uncertain. Objective To investigate the efficacy and safety of acupuncture as adjunctive therapy to antianginal therapies in reducing frequency of angina attacks in patients with chronic stable angina. Design, Setting, and Participants In this 20-week randomized clinical trial conducted in outpatient and inpatient settings at 5 clinical centers in China from October 10, 2012, to September 19, 2015, 404 participants were randomly assigned to receive acupuncture on the acupoints on the disease-affected meridian (DAM), receive acupuncture on the acupoints on the...
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Effect of Gua Sha therapy on patients with diabetic peripheral neuropathy: A randomized controlled trial

Abstract OBJECTIVE: To examine the effect of Gua Sha therapy in the treatment of diabetic peripheral neuropathy (DNP). DESIGN: An open-label randomized controlled study was conducted with usual care as the control (60 subjects in Gua Sha group and 59 subjects in usual care group). Outcome measures included Toronto Clinical Scoring System (TCSS), Vibration Perception Threshold (VPT), Ankle Brachial Index (ABI), and fasting plasma glucose (FPG). There were 12 consecutive sessions of Gua Sha, one session per week. RESULTS: After the first cycle of Gua Sha intervention, only performance of sensory function measured by the VPT, and peripheral artery disease...
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Acupuncture for the Treatment of Cardiovascular Diseases: A Systematic Review

Abstract Acupuncture, for the westerns countries, is an innovative and low-cost therapy for treatment and prevention of cardiovascular diseases (CVDs). However, most of its effects and mechanisms are poorly understood. Thus, the objective of this work was to systematically review the literature regarding the clinical effects of acupuncture for the treatment and prevention of CVDs. A search for papers published in English or Portuguese in the past 20 years was conducted at PubMed, SciELO, and PEDro databases. Clinical trials conducted on the effects of acupuncture were included in this review. Two reviewers extracted the data independently from the remaining 17 articles after screening. The most...
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2 g Ingwer senken Cholesterinspiegel

Original Titel: The effect of ginger supplementation on lipid profile: A systematic review and meta-analysis of clinical trials Erhöhte Blutfette stellen einen großen Risikofaktor für die koronare Herzkrankheit dar. Ingwer könnte helfen, diese zu senken, wie die vorliegende Studie zeigte. Hierbei schien jedoch weniger mehr zu sein. Erhöhte Blutfettwerte sind eine Hauptursache für die koronare Herzkrankheit. Diese zu senken ist somit wichtig, um der KHK vorzubeugen. Doch auch bei bereits bestehender Erkrankung ist es wichtig, eventuell zu hohe Blutfette zu senken, um das Risiko für Folgeerkrankungen wie z. B. einen Herzinfarkt zu reduzieren. In der Regel werden hierfür Statine eingesetzt, doch auch Ingwer wird eine blutfettsenkende Wirkung...
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Neue Präventionschance: Behandlung von Bluthochdruck mit traditioneller chinesischer Medizin kann möglicherweise das Demenzrisiko senken

Original Titel: Association of traditional Chinese medicine therapy and the risk of dementia in patients with hypertension: a nationwide population-based cohort study. In früheren Studien wurde ein erhöhten Demenzrisiko von Bluthochdruckpatienten berichtet. Bluthochdruck wird oft mit alternativen Methoden, in Taiwan am häufigsten mit Traditioneller chinesischer Medizin (TCM), behandelt. Bisher ist es jedoch unklar, ob diese Behandlung auch das Demenzrisiko der Patienten senken könnte. Ziel der taiwanesischen Studie von Chen und Kollegen (2017) war es daher, den Effekt von TCM auf das Demenzrisiko bei Bluthochdruckpatienten zu untersuchen. Die Studie rekrutierte 143.382 Patienten aus der Taiwanesischen nationalen Krankenversicherungs-Forschungsdatenbank, bei denen gerade Bluthochdruck...
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Hypertensive patients benefit from acupuncture treatments, UCI study finds

Patients with hypertension treated with acupuncture experienced drops in their blood pressure that lasted up to a month and a half, researchers with the Susan Samueli Center for Integrative Medicine have found. Their work is the first to scientifically confirm that this ancient Chinese practice is beneficial in treating mild to moderate hypertension, and it indicates that regular use could help people control their blood pressure and lessen their risk of stroke and heart disease. “This clinical study is the culmination of more than a decade of bench research in this area,” said Dr. John Longhurst, a University of California,...
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Laser acupuncture protocol for essential systemic arterial hypertension: randomized clinical trial

ABSTRACT Objectives: to evaluate the efficacy of a laser acupuncture protocol developed and applied by nurses in arterial hypertension patients. Method: randomized, multicenter, triple-blind and two-armed clinical trial. The sample consisted of 102 participants, 51 per arm, both sexes, aged between 30 and 75 years, undergoing drug therapy for a year or more, with difficulty to control blood pressure, maintaining regular measures >140×90 mmHg. Participants underwent six standard or simulated laser-acupuncture sessions, for 24 minutes, within a period of six weeks. Descriptive analyzes expressed as frequencies of occurrences, means and medians were used, and analysis of the association between variables...
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Effect of Acupuncture or Massage on Health-Related Quality of Life of Hemodialysis Patients

Abstract Objective: The purpose of this study was to evaluate the effect of acupuncture and massage on health-related quality of life (HR-QOL) among end stage renal disease (ESRD) patients. Design: Pre-post test design. Setting: A hemodialysis (HD) unit located in a university hospital. Intervention: Participants were given the option to choose between 20 min sessions of massage or acupuncture therapy once a week for 8 weeks by licensed acupuncturists and massage therapists while undergoing their usual HD session in the University of California, San Diego Chronic HD unit. Outcome measures: Participants were asked to complete pre- and postintervention surveys, which consisted...
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Sheng Mai San beneficial for heart failure

A Cochrane Database systematic review from China suggests that the herbal formula Sheng Mai San (SMS – Generate the Pulse Powder) may exert a positive effect on heart failure, especially when used alongside usual medical treatment. SMS consists of three herbs: Ren Shen (Ginseng Radix), Mai Men Dong (Radix Ophiopogonis) and Wu Wei Zi (Fructus Schisandrae Chinensis). The authors included a total of 14 RCTs (858 patients) in their review. Of these, 11 trials compared SMS plus usual treatment with usual treatment alone, and three trials compared SMS with placebo. Meta-analysis showed that patients taking SMS plus usual treatment were...
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Rotwurz-Salbei schützt das Herz

Diabetes-Patienten mit koronarer Herzkrankheit könnten profitieren Rotwurzel-Salbei könnte das Risiko für Herz-Kreislauf-Erkrankungen senken. Besonders bereits betroffene Diabetes-Patienten würden profitieren. Die Herzen von Diabetes-Patienten sind besonders gefährdet, da ihr Risiko, eine Herz-Kreislauf-Erkrankung zu entwickeln, erhöht ist. Chinesische Wissenschaftler haben im Rahmen einer (vorläufigen) kontrollierten Studie Hinweise auf die herzschützenden Eigenschaften des Rotwurzel-Salbeis gefunden. Der auch als Danshen bezeichnete Rotwurzel-Salbei (Salvia miltiorrhiza) stellt eine der wichtigsten Pflanzen in der Traditionellen Chinesischen Medizin dar. Besonders bewährt hat sich die Wurzel dieser Unterart des Salbeis in der Behandlung von Erkrankungen des Stoffwechsels und des Herz-Kreislauf-Systems. An 62 Diabetes (Typ 2)-Patienten mit koronarer Herzkrankheit wurde...
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Neiguan P-6 stimulation affects cardiovacular system via brain reflexes

A review paper by Chinese authors has focused on the neurophysiological basis of the effects of Neiguan P-6 stimulation on cardiovascular mechanisms. The review summarises experimental studies, which show that specific brain regions and neural pathways are involved in attenuating sympathoexcitatory cardiovascular reflex responses, following acupuncture. (The influence of PC6 on cardiovascular disorders: a review of central neural mechanisms. Acupunct Med. 2012 Mar;30(1):47-50). Quelle:

Needling Shenmen HE-7 affects heart rate variability

Chinese scientists have shown that acupuncture at Shenmen HE-7 can affect cardiac autonomic neural regulation in healthy subjects. One hundred and twenty subjects were divided into four groups and received four different interventions: verum acupuncture at Shenmen HE-7; non-penetrating sham acupuncture at Shenmen HE-7; verum acupuncture at a sham point; and no acupuncture. Heart rate variability (HRV), which is a measure of the balance between sympathetic and parasympathetic mediators of heart rate, was recorded 10 minutes before, during and after each intervention. The results showed that, compared with sham needling and no acupuncture controls, verum acupuncture at Shenmen HE-7 increased...
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Needling LIV-3 reduces blood pressure via effect on brain network involved in emotional processing

Acupuncture at Taichong LIV-3 leads to decreases in systolic blood pressure, which can be correlated with increases in connectivity between areas of the brain related to emotional processing and blood pressure control. Researchers from China randomly divided 30 hypertensive patients into a verum acupuncture group (needled at Taichong LIV-3) and a sham acupuncture group (needled at a non-acupuncture point on the anterior thigh). Significant differences in systolic blood pressure were found only in the verum group. Examination of fMRI scans showed that acupuncture at LIV-3 specifically increased activity in the frontal lobe of the brain, as well as functional connectivity...
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Long-Lasting Reduction of Blood Pressure by Electroacupuncture in Patients with Hypertension: Randomized Controlled Trial

ABSTRACT Background: Acupuncture at specific acupoints has experimentally been found to reduce chronically elevated blood pressure. Objective: To examine effectiveness of electroacupuncture (EA) at select acupoints to reduce systolic blood pressure (SBP) and diastolic blood pressures (DBP) in hypertensive patients. Design: Two-arm parallel study. Patients: Sixty-five hypertensive patients not receiving medication were assigned randomly to one of the two acupuncture intervention (33 versus 32 patients). Intervention: Patients were assessed with 24-hour ambulatory blood pressure monitoring. They were treated with 30-minutes of EA at PC 5-6+ST 36-37 or LI 6-7+GB 37-39 once weekly for 8 weeks. Four acupuncturists provided single-blinded treatment....
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Herbs for Atrial Fibrillation

Abstract Herbal medicines show much promise for helping patients with atrial fibrillation (AF). Nao Xin Tong Nang (Brain and Heart Connected Capsule) formula with aspirin, lumbrokinase, and nattokinase are all natural anticoagulants, with varying degrees of evidence supporting their use or potential use in AF patients. The modern Chinese herbal formula Wen Xin Ke Li looks promising for maintaining sinus rhythm in paroxysmal AF patients, as does Shen Song Yang Xin Capsule. Anti-arrhythmic herbs, both for heart rate and for heart rhythm control (as well as preventing paroxysmal AF from recurring), generally usedhistorically and not studied in clinical trials but...
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Elektroakupunktur senkt nachweislich Bluthochdruck

Ein erhöhter Blutdruck steigert unter anderen das Risiko, einen Herzinfarkt oder eine Herzinsuffizienz zu erleiden. Eine randomisierte kontrollierte Studie (2015) der University of California, des East Hospitals in Shanghai und der Southern California University of Health Sciences ergab, dass die Elektroakupunktur bewährter Akupunkturpunkte den Blutdruck zuverlässig senken kann. Zusammenfassung der Studie Die Studie wurde mit 65 Patienten durchgeführt, die unter leichtem bis mittelschwerem Bluthochdruck litten, und keinerlei Blutdruckmedikamente einnahmen. Die Forscher teilten die Patienten in eine Kontrollgruppe und eine Behandlungsgruppe auf, und behandelten beide verblindet über 8 Wochen einmal wöchentlich mit Elektroakupunktur. Die Kontrollgruppe erhielt eine Sham-Akupunktur an den Punkten...
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Electro-acupuncture reduces blood pressure

A group of American researchers have found that electro-acupuncture (EA) has a significant and long-lasting blood pressure–lowering effect in hypertensive patients with chronically elevated blood pressure (BP). Sixty-five patients with mild to moderate hypertension not receiving medication were randomly assigned to one of two acupuncture interventions. They were treated once weekly for eight weeks with 30-minutes of EA at either a set of active treatment acupoints (Jianshi P-5 – Neiguan P-6, plus Zusanli ST-36 – Shangjuxu ST-37) or a set of control acupoints (Pianli L.I.-6 – Wenliu L.I.-7, plus Guangming GB-37- Xuanzhong GB-39). Patients were assessed with 24-hour ambulatory blood...
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Comparative effectiveness of acupuncture and antiarrhythmic drugs for the prevention of cardiac arrhythmias: a systematic review and meta-analysis of randomized controlled trials

Abstract Introduction and objectives. This study was designed to systematically evaluate the effectiveness of acupuncture treatment for arrhythmia compared to existing drug therapy. Methods. Randomized controlled trials (RCTs) were identified through searches of the MEDLINE, CNKI, Embase, and Cochrane databases (1970 through 2016) and hand searches of cross-references from original articles and reviews. Clinical trials that randomized arrhythmia patients to acupuncture therapy vs. conventional drugs, sham acupuncture, or bed rest were included for analysis. Results. A total of 13 trials with 797 patients met the criteria for analysis. The results of the meta-analysis showed no statistically significant difference between acupuncture and conventional...
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Acupuncture reduces blood pressure in medicated hypertensive patients

Patients with high blood pressure who are taking anti-hypertensive medication may benefit from adjunctive acupuncture treatment, according to a small study carried out in Turkey. Investigators studied 34 patients who had been on anti-hypertensive drug therapy for at least 24 months and who were experiencing side-effects such as fatigue, dizziness, weakness, headache, joint pain, sleeping problems, oedema and depression. The participants underwent 15 acupuncture sessions (every two days for one month), without alteration to their diet, physical activity or use of anti-hypertensive drugs. Points needled were Taixi KID-3, Taichong LIV-3, Yinlingquan SP-9, Hegu L.I. 4, Shenmen HE-7, Zusanli ST-36, Sanyinjiao...
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Acupuncture prevents recurrence of arrhythmia after cardioversion

An Italian team has found that acupuncture treatment prevents arrhythmic recurrences after cardioversion in patients with persistent atrial fibrillation (AF). They studied 80 patients who had persistent AF after sinus rhythm had been restored using electrical cardioversion. Twenty-six subjects who were already on amiodarone (an anti-arrhythmic drug) treatment constituted the AMIO reference group. The remaining patients were randomly allocated to receive acupuncture (ACU), sham acupuncture (ACU-sham), or neither acupuncture nor anti-arrhythmic therapy (CONTROL). Patients in the ACU and ACU-sham groups received ten weekly acupuncture sessions, using the points Neiguan P-6, Shenmen HE-7 and Xinshu BL-15. During a 12-month follow-up, AF...
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Acupuncture Controls Hypertension, Provides Neuroprotection

Quelle (16 June 2017): Researchers conclude that acupuncture reduces hypertension and prevents brain damage due to chronic high blood pressure. A controlled laboratory investigation finds acupuncture effective for the regulation of blood pressure while simultaneously preventing excessive cell death in the brain. In a quantification of acupuncture’s effective mechanisms, researchers identified important biological responses elicited by acupuncture responsible for producing therapeutic benefits. The research team of Lu et al. identified biochemical responses elicited by the application of three acupuncture techniques. Reinforcing twirling, reducing twirling, and needle retention techniques resulted in reduced blood pressure and downregulation of cell death in...
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Acupuncture Controls Hypertension In Groundbreaking Trial

Quelle (21 November 2017): Researchers find acupuncture effective for the treatment of hypertension in middle-aged adults. In a groundbreaking eight week acupuncture trial, an international research team documents that acupuncture causes significant improvements in both brachial blood pressure and central aortic blood pressure in hypertensive middle-aged adults. [1] The scientific investigation was a collaboration between researchers from Larkin Community Hospital (Miami, Florida), Marymount University (Arlington, Virginia), Nosov Magnitogorsk State Technical University (Russia), and Moscow Financial and Law University (Russia). The researchers note that prior investigations find acupuncture effective for the treatment of hypertension. [2,3] However, they add that this...
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