Auswirkungen eines modifizierten Wendan-Decokts in Kombination mit Akupunktur auf Entzündungsfaktoren und die Immunfunktion bei Urtikariapatienten
Abstract
This study aimed to explore the effects of modified “Wendan Decoction” combined with acupuncture on serum inflammatory markers and immune function in patients suffering from urticaria. A total of 150 urticaria patients admitted to our hospital were randomly assigned to two groups: the observation group (n = 75) and the control group (n = 75). The control group received levocetirizine tablets, while the observation group was treated with modified Wendan Decoction along with acupuncture. Following treatment, the observation group demonstrated a higher clinical efficacy compared to the control group, with a statistically significant difference (P < 0.05). Both groups experienced reductions in symptom scores, including erythema, burning sensation, pruritus, wheals, fever accompanied by epigastric pain, nausea and vomiting, fatigue, and poor appetite. However, the observation group showed significantly lower symptom scores than the control group (P < 0.05). Additionally, levels of IL-4, IL-10, IL-25, IL-33, and IFN-γ decreased in both groups after treatment, but the observation group exhibited lower levels than the control group, again with a statistically significant difference (P < 0.05). The recurrence rate was notably lower in the observation group compared to the control group (P < 0.05). The combination of modified Wendan Decoction and acupuncture effectively reduces serum inflammatory markers and enhances immune function in patients with urticaria. This treatment demonstrates significant clinical effectiveness and holds potential for broader application in clinical settings.
Autoren
Tian, Z., Dong, J., Wang, Y.
Journal
Springer Nature Link
Link: https://doi.org/10.3389/falgy.2025.1600032
Verwendete Punkte:
- Gallenblase 20, 31
- Dreifach Erwärmer 5
- Dickdarm 11
- Du Mai 24
- Dünndarm 9
- Magen 36
- Leber 3
- EX-LE 13
WEN DAN TANG „Dekokt, das die Gallenblase wärmt“
Reguliert das Qi, transportiert Schleim, klärt die Gallenblase und harmonisiert den Magen
Zhu Ru 竹茹 (Caulis Bambusae in Taeniis)
Zhi Shi 枳实 (Fructus Aurantii Immaturus)
Fa Ban Xia 法半夏 (Rhizoma Pinelliae Praep)
Chen Pi 陈皮 (Pericarpium Citri Reticulatae)
Bai Fu Ling 茯苓 (Poria Alba)
Sheng Gan Cao 甘草 (Radix Glycyrrhizae)
Sheng Jiang 生姜 (Rhizoma Officinalis Zingiberis Recens)
QUELLE:
Tian, Z., Dong, J., & Wang, Y. (2025). Effects of modified Wendan Decoction combined with acupuncture on inflammatory factors and immune function in urticaria patients. Archives of Dermatological Research, 317(1), 696.