Akupunktur in Kombination mit Mirabegron (Betmiga) ist wirksam bei der Behandlung der überaktiven Blase: eine prospektive randomisierte kontrollierte Studie
Abstract
Purpose
To investigate the efficacy and safety of acupuncture combined with mirabegron for overactive bladder (OAB) treatment.
Methods
This prospective cohort study took place at Ganzhou People’s Hospital. One hundred and sixty patients with OAB were divided into control and treatment groups at a ratio of 1:1 using a randomized number-table method. The control group was administered mirabegron alone (50 mg/day), while the treatment group was administered mirabegron orally and acupuncture at Guanyuan (CV4), Zhongji (CV3), and Sanyinjiao (SP6). The Overactive Bladder Syndrome Score (OABSS), voiding, urgency, nocturia, incontinence, and incidence of related adverse events were compared between the two groups at baseline and after 4, 8, and 12 weeks of treatment.
Results
Of the160 patients, 10 were lost; the remaining 74 and 76 patients were included in the control and treatment groups, respectively. The mean numbers of occurrences of voiding, urgency, nocturia, and incontinence along with OABSS of the patients in the two groups improved after 4, 8, and 12 weeks of treatment compared with those before treatment, with the therapeutic effect more significant in the treatment group (P < 0.05). The overall efficacy rates in the control and treatment groups were 81.08% and 94.74%, respectively (P = 0.022). The incidence of total adverse events was not significantly different between groups after 12 weeks of treatment (P > 0.05); no serious adverse reactions occurred in either group.
Conclusions
Acupuncture combined with mirabegron was effective for OAB treatment. This treatment combination was superior to mirabegron alone without significant increases in adverse effects.
Autoren
Deng Xiaolin, Xie Baoquan, Huang Xin, Kuang Jin & Yao Lei
Journal
African Journal of Urology
Link: https://doi.org/10.1186/s12301-025-00514-w
Verwendete Punkte:
- Ren Mai 3, 4
- Milz-Pankreas 6
QUELLE:
Xiaolin, D., Baoquan, X., Xin, H., Jin, K., & Lei, Y. (2025). Acupuncture combined with mirabegron is efficacious for the treatment of overactive bladder: a prospective randomized controlled trial. African Journal of Urology, 31(1), 43. https://doi.org/10.1186/s12301-025-00514-w