A Chinese herbal formula has been shown to reduce serum uric acid (sUA) levels and prevent recurrence of acute gouty arthritis. In a randomised placebo-controlled trial, Chinese researchers evaluated the effects of compound tufuling oral liquid (CoTOL – Tu Fu Ling [Rhizoma Smilacis], Bi Xie [Rhizoma Dioscoreae], Jiang Huang [Rhizoma Curcumae Longae], Xi Xian Cao [Herba Siegesbeckiae], Yan Hu Suo [Rhizoma Corydalis], Yi Yi Ren [Semen Coicis], Sang Ji Sheng [Herba Taxilli], Yu Mi Xu [Stigma Maydis]) on 210 patients with gout over a 12-week treatment period. At the end of the 12-week treatment, the average decrease in serum uric acid was significantly greater in the treatment group compared with the control group (74.26 μmol/L versus 28.81 μmol/L). The gouty arthritis recurrence rate in the treatment group was also significantly lower than that of the control group (21.93% versus 50.88% from week 6 to 12, and 38.5% versus 63.16% from baseline to week 12).
Hypouricemic and arthritis relapse-reducing effects of compound tufuling oral-liquid in intercritical and chronic gout: A double-blind, placebo-controlled, multicenter randomized trial.
Medicine (Baltimore). 2017 Mar;96(11):e6315.