Xin Yi San (XYS, magnolia flower powder) reduces nasal symptoms in patients with perennial allergic rhinitis (AR) due to its diverse immunomodulatory effects. One hundred and eight Taiwanese patients with AR received either XYS or a placebo for three months. The investigators found that XYS attenuated the nasal symptoms of sneezing, rhinorrhoea and nasal congestion through reduction of nasal airflow resistance and increase in the cross-sectional area of nostrils. They also observed that XYS exerted diverse in vitro immunomodulatory effects, including suppression of serum IgE levels and increased production of the cytokines IL-10, sICAM-1 and IL-8. (Traditional Chinese medicine, Xin-yi-san, reduces nasal symptoms of patients with perennial allergic rhinitis by its diverse immunomodulatory effects. Int Immunopharmacol. 2010 Aug;10(8):951-8).