Studien zum Thema Gehirn und Nervensystem

Auswirkungen der manuellen Akupunktur im Vergleich zur Scheinakupunktur bei Patienten mit Depressionen nach Schlaganfall: Eine randomisierte klinische Studie Abstract Background Post-stroke depression (PSD) is a prevalent psychiatric complication in stroke patients, severely reducing quality of life and delaying social recovery in stroke survivors. Clinical studies have shown that acupuncture can be used as an alternative approach for PSD. The aim of this study was to examine the safety, efficacy, and electroencephalogram (EEG) mechanism of acupuncture in treating PSD patients. Methods From October 28, 2022 to May 16, 2023, this single-center, single-blind, randomized clinical trial was conducted at the Second Affiliated...Weiterlesen

Die veränderte funktionelle Konnektivität des hypothalamischen Netzwerks bei chronischer Schlaflosigkeit und die regulierende Wirkung der Akupunktur: eine randomisierte kontrollierte bildgebende Studie Abstract Background The hypothalamus has been recognized as a core structure in the sleep-wake cycle. However, whether the neuroplasticity of the hypothalamus is involved in the acupuncture treatment of insomnia remains elusive. Methods We recruited 42 patients with chronic insomnia disorder (CID) and 23 matched healthy controls (HCs), with CID patients randomly assigned to receive real acupuncture (RA) or sham acupuncture (SA) for four weeks. Insomnia severity was evaluated using the Pittsburgh Sleep Quality Index (PSQI) score, and the...Weiterlesen

Abstract To investigate the efficacy of laser acupuncture and photobiomodulation therapy in alleviating symptoms among patients diagnosed with Bell’s palsy with duration of greater than 8 weeks. The randomized controlled trial has been performed from May 2021 to April 2023. Patients were eligible who had Bell’s palsy with duration of greater than 8 weeks on out-patient Department of Otorhinolaryngology in Beijing Tongren Hospital. The laser acupuncture group received class IV laser treatment for 3 times per weeks, a total of 72 times. The control group received the same treatment procedure except the laser parameter. The primary outcome measures comprised House-Brackmann facial nerve grading system and electroneurography....Weiterlesen

Abstract Background To observe the effects of conventional theatre nursing combined with transcutaneous electrical acupoint stimulation (TEAS) on postoperative cognitive dysfunction (POCD) in elderly total knee arthroplasty (TKA) patients. Methods Forty elderly TKA patients were randomly divided into a conventional nursing (control) group and a TEAS group. Using conventional nursing, TEAS was used to stimulate the „Zusanli“ and „Sanyinjiao“ in the healthy leg of patients in the TEAS group. All patients received mini-mental (MMSE) scores 1 day before surgery (T0) and 1, 3, and 7 days after surgery (T1, T3, T7). Plasma levels of interleukin-1 (IL-1β), interleukin-6 (IL-6), tumor necrosis...Weiterlesen

Abstract Background The incidence of nausea and vomiting following craniotomy is high, and pericardium 6 (P6; Neiguan) acupoint stimulation is an important strategy for treating postoperative nausea and vomiting (PONV). Here, we aimed to evaluate the efficacy of transcutaneous electrical acupoint stimulation (TEAS) at P6 as an adjunct to antiemetic drugs to prevent PONV after craniotomy. Materials and methods This randomized placebo-controlled trial enrolled 120 patients scheduled for craniotomy. The enrolled patients were randomly assigned to a TEAS or sham TEAS group. The incidence of PONV, pain score, and postoperative remedial treatment with antiemetics and analgesics at 0-2, 2-6, and...Weiterlesen

Abstract Importance Motor aphasia is common among patients with stroke. Acupuncture is recommended as an alternative therapy for poststroke aphasia, but its efficacy remains uncertain. Objective To investigate the effects of acupuncture on language function, neurological function, and quality of life in patients with poststroke motor aphasia. Design, setting and participants This multicenter, sham-controlled, randomized clinical trial was conducted in 3 tertiary hospitals in China from October 21, 2019, to November 13, 2021. Adult patients with poststroke motor aphasia were enrolled. Data analysis was performed from February to April 2023. Interventions Eligible participants were randomly allocated (1:1) to manual acupuncture (MA) or sham acupuncture (SA) groups. Both groups underwent language...Weiterlesen

Abstract Introduction Multiple sclerosis (MS) is a progressive disease of the central nervous system that can result in highly variable effects on mobility and sensorimotor function. Persons with MS (pwMS) often use complementary and alternative approaches, such as acupuncture, to address these symptoms. However, studies of acupuncture on these symptoms have been hindered by methodologic flaws, which have limited the ability to draw conclusions about its efficacy. The purpose of this study was to examine the feasibility of an acupuncture intervention on a wide range of sensorimotor and mobility measurements in pwMS. Methods Using a randomized crossover design, subjects experienced...Weiterlesen

Abstract Objectives To compare the effects of acupuncture and medical training therapy in combination or individually with usual care on quality of life, depression, and anxiety in patients with tension-type headache. Methods In this single-center, prospective, randomized, controlled, unblinded trial, 96 adults (38.7(+/−13.3) years of age; 75 females/20 males/one dropout) with frequent episodic or chronic tension-type headache were randomized to one of four treatment groups (n = 24). The treatment groups received six weeks of either acupuncture or medical training therapy as monotherapies or in combination (12 interventions each), or usual care. We assessed depressiveness (PHQ-9), anxiety (GAD-7), and health-related quality of...Weiterlesen

Abstract Background Acupuncture has a long history of being used in Chinese medicine for the treatment of migraine. However, molecular biomarkers for diagnosis and prognosis of migraine and its treatment are lacking. This study aimed to explore whether acupuncture could regulate differentially expressed exosomal miRNAs between patients with migraine without aura (MWoA) and healthy controls (HCs) and to identify diagnostic biomarkers that helped differentiate MWoA patients from HCs and identify prognostic biomarkers that helped to predict the effect of acupuncture. Methods Here, we isolated serum exosomes from patients with MWoA and HCs before and after true and sham acupuncture treatment....Weiterlesen

Abstract Importance One of the ordinary manifestations of Parkinson disease (PD) is anxiety, which remains untreated. Anxiety is closely associated with the accelerated progression of PD. Efficacy of acupuncture for anxiety has been reported. However, to date, there are no data on acupuncture’s effectiveness on anxiety for patients with PD. ObjectiveTo investigate the effect of acupuncture vs sham acupuncture for treating anxiety in patients with PD. Design, Setting, and ParticipantsThis is randomized, double-blinded, clinical trial enrolled patients between June 20, 2021, and February 26, 2022. Final follow-up was April 15, 2022. Patients with Parkinson disease and anxiety were allocated randomly (1:1)...Weiterlesen

Abstract ObjectiveThe objective of this study was to investigate the difference between the clinical effectiveness of two acupuncture methods in the treatment of acute ischemic stroke (AIS) and provide more evidence-based medical evidence of acupuncture’s effectiveness in stroke rehabilitation. MethodsWe conducted an outcome assessor-and data analyst-blinded, randomized, and controlled trial. Seventy-two participants were randomly allocated to the observation group and control group with a 1 : 1 allocation ratio by the generating of a random number table.The observation group received the „Xingnao kaiqiao“ acupuncture method combined with „Temporal three needles,“ and the control group received conventional acupuncture „Scalp acupuncture“ combined...Weiterlesen

Abstract BackgroundAcupuncture is commonly used in Traditional Chinese Medicine for treatment of diabetic peripheral neuropathy (DPN), but data from randomized controlled trials are rare. MethodsThis randomized, placebo-controlled, partially double-blinded clinical trial randomly assigned adults with confirmed type 2 diabetes-induced DPN to receive 10 sessions of needle acupuncture, laser acupuncture, or placebo laser acupuncture for 10 consecutive weeks. Treatment was provided at bilateral acupoints Ex-LE-10 (Bafeng), Ex-LE-12 (Qiduan), and ST-34 (Lianqiu). Neurological assessments, including nerve conduction studies (NCS) of sural and tibial nerves, were performed at baseline and weeks 6 and 15. Primary outcome was delta of sural sensory nerve action...Weiterlesen

Autor: Shabei Xu, Lingling Yu, Xiang Luo, Minghuan Wang, Guohua Chen, Qing Zhang, Wenhua Liu, Zhongyu Zhou, Jinhui Song, Huitao Jing, Guangying Huang, Fengxia Liang, Hua Wang, Wei Wang Abstract Objective: To assess the efficacy of manual acupuncture as prophylactic treatment for acupuncture naive patients with episodic migraine without aura.  Design: Multicentre, randomised, controlled clinical trial with blinded participants, outcome assessment, and statistician. Setting: Seven hospitals in China, 5 June 2016 to 15 November 2018.  Participants: 150 acupuncture naive patients with episodic migraine without aura.  Interventions: 20 sessions of manual acupuncture at true acupuncture points plus usual care, 20 sessions of non-penetrating sham acupuncture at heterosegmental...Weiterlesen

Autor: Junying Zhang, Caishui Yang, Dongfeng Wei, He Li, Elaine Lai-Han Leung, Qingqiong Deng, Zhen Liu, Xing-Xing Fan, Zhanjun Zhang Abstract Mild cognitive impairment (MCI), regarded as the prodromal stage before the clinical phase of Alzheimer’s disease (AD), has been considered for early intervention. Unfortunately, many trials in this stage with drugs with single-target turned out to be little or no effect. Multi-targeting in nature based on the theory of Traditional Chinese Medicine (TCM) offers another prospect for intervention. Together with advanced functional magnetic resonance imaging (fMRI) technique for more sensitive and objective evaluation, we investigated the long-term therapeutic effects of...Weiterlesen

Abstract Background Propranolol is recommended as first-line treatment for preventing migraine attacks; acupuncture has not been compared with propranolol in a head-to-head trial. Objective To compare acupuncture with propranolol using indirect treatment comparison meta-analysis. Method We searched MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials (CENTRAL). Randomized controlled trials comparing acupuncture or propranolol with sham acupuncture, placebo, waiting-list control or usual care were included. We extracted information from the included trials using a standardized extraction form. The primary outcome was migraine episodes. The secondary outcomes included migraine days, migraine frequency, and adverse events. Results We included 19 RCTs (n =...Weiterlesen

Abstract OBJECTIVE: To examine the effect of Gua Sha therapy in the treatment of diabetic peripheral neuropathy (DNP). DESIGN: An open-label randomized controlled study was conducted with usual care as the control (60 subjects in Gua Sha group and 59 subjects in usual care group). Outcome measures included Toronto Clinical Scoring System (TCSS), Vibration Perception Threshold (VPT), Ankle Brachial Index (ABI), and fasting plasma glucose (FPG). There were 12 consecutive sessions of Gua Sha, one session per week. RESULTS: After the first cycle of Gua Sha intervention, only performance of sensory function measured by the VPT, and peripheral artery disease...Weiterlesen

Abstract OBJECTIVE: To explore the acupoint selection rules of acupuncture for Alzheimer’s disease (AD) in modern clinical practice by complex network technology. METHODS: The relevant articles of clinical trials were retrieved from CNKI published before December 2017. Using Microsoft Excel 2010, the database was established. Using Gephi 0.8.2 software, the complex network mode was built and its topological structure was analyzed. RESULTS: Finally, 81 articles were eligible and 114 acupoint prescriptions were extracted. The constructed complex network of acupoint prescriptions for AD was characteristics as small world effect and scale-free property, the crucial acupoints included Baihui (GV 20), Sishencong (EX-HN...Weiterlesen

A systematic review and meta-analysis of RCTs Background Bell’s palsy or idiopathic facial paralysis is an acute facial paralysis caused by the inflammation of facial nerve. Several previous studies showed that acupuncture was beneficial in the treatment of facial paralysis. However, its effectiveness is still controversial compared with drug therapy. Therefore, this systematic review and meta-analysis was performed to assess the efficacy of acupuncture for Bell’s palsy. Methods This is a systematic review and meta-analysis of clinical studies among patients with Bell’s palsy. We did a systematic literature search in PubMed, Embase, and the Cochrane Register of Controlled Trials to identify studies comparing the efficacy of acupuncture and drug treatment in treating facial paralysis. The search was last updated on July...Weiterlesen

Abstract PURPOSE: Chemotherapy-induced peripheral neuropathy is a complex side effect with few available treatment options. The aim of the study was to test the effectiveness of an 8-week course of acupuncture in the management of chemotherapy-induced peripheral neuropathy in cancer patients who were receiving or had received neurotoxic chemotherapy. METHODS: Randomized assessor-blinded controlled trial with 2 arms; one arm received acupuncture twice weekly for 8 weeks, while the other arm was a wait-list control group receiving only standard care. Primary outcome was pain intensity and interference over the past week using the Brief Pain Inventory at the end of the...Weiterlesen

Traditional preparation of three herbs relieves and reduces symptoms of disease in mice and tests on humans are encouraging, study finds PUBLISHED: Sunday, 07 December, 2014, 4:47am A traditional Chinese medicine known as smart soup (聰明湯) could help in the fight against Alzheimer’s disease, scientists on the mainland believe. The simple treatment helped relieve and even reverse Alzheimer’s symptoms in mice that had been genetically modified to acquire the disease, researchers with the Chinese Academy of Sciences‘ Institute of Biochemistry and Cell Biology in Shanghai found. The rodents began to show improvements after just six days of being fed the...Weiterlesen

Original Titel: Association of traditional Chinese medicine therapy and the risk of dementia in patients with hypertension: a nationwide population-based cohort study. In früheren Studien wurde ein erhöhten Demenzrisiko von Bluthochdruckpatienten berichtet. Bluthochdruck wird oft mit alternativen Methoden, in Taiwan am häufigsten mit Traditioneller chinesischer Medizin (TCM), behandelt. Bisher ist es jedoch unklar, ob diese Behandlung auch das Demenzrisiko der Patienten senken könnte. Ziel der taiwanesischen Studie von Chen und Kollegen (2017) war es daher, den Effekt von TCM auf das Demenzrisiko bei Bluthochdruckpatienten zu untersuchen. Die Studie rekrutierte 143.382 Patienten aus der Taiwanesischen nationalen Krankenversicherungs-Forschungsdatenbank, bei denen gerade Bluthochdruck...Weiterlesen

Abstract Objective: To observe the clinical efficacy of acupuncture therapy and carbamazepine therapy for primary trigeminal neuralgia. Methods: A total of 150 patients with primary trigeminal neuralgia treated in Department of Rehabilitation Medicine of Linyi Central Hospital from January 2010 to December 2016 were selected. They were divided into acupuncture group (n=75) and drug group (n=75). The patients in the acupuncture group received acupuncture based on the shape of trigeminal nerve once daily with 10 days as a treatment course. The results were observed after two treatment courses. Those in the drug group took 0.1 g carbamazepine three times daily...Weiterlesen

Abstract BACKGROUND: Bortezomib-induced peripheral neuropathy (BIPN) is a common and debilitating side effect. Our pilot study demonstrated that acupuncture is safe and can decrease total neuropathic symptoms. However, there is lack of knowledge in which individual BIPN symptoms benefited from acupuncture. PURPOSE: To characterize individual symptoms reduced by acupuncture in patients with BIPN. METHODS: Patients with multiple myelomatreated with bortezomib who developed BIPN grade 2 or above, based on National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE), were enrolled and received 10 acupuncture treatments over 10 weeks. Self-reported BIPN-associated symptoms assessments were collected weekly at baseline, during,...Weiterlesen

Abstract Objective: Painful diabetic peripheral neuropathy (PDN) is one of the most common complications of diabetes. In patients with PDN, greater pain intensity leads to poorer quality of life, sleep, function, and work productivity (1–3). According to the clinical practice guideline, electrical stimulation is probably effective and should be considered for the treatment of PDN (evidence level B) (4). The aim of this study is to evaluate the effectiveness and safety of electroacupuncture (EA) for the management of PDN in patients with type 2 diabetes Methods: This multicenter, randomized, assessorblinded, controlled trial was conducted between June 2014 and March 2016...Weiterlesen

Acupuncture benefits patients suffering from hemiplegia (unilateral paralysis) after a stroke. Traditional Chinese Medicine Hospital of Baoji researchers compared daily exercise monotherapy with acupuncture plus daily exercises. Patient outcomes were consistently superior in the combined therapy group, demonstrating that the addition of acupuncture to the daily exercise treatment regimen improves clinical outcomes. The researchers conclude that acupuncture plus rehabilitation exercises improves motor function and cerebral blood flow, making it an effective intervention for post-stroke hemiplegia. [1] Objective and subjective data were the basis for the conclusions. Blood flow changes in the brain were measured with a transcranial Doppler device, a...Weiterlesen

Acupuncture is an effective treatment modality for the alleviation of Parkinson’s disease. Zhejiang University of Traditional Chinese Medicine (Hangzhou, China) researchers conducted a study comparing the effects of drug therapy as a standalone procedure with acupuncture plus drug therapy in an integrated treatment protocol. Based on the data, the researchers conclude that acupuncture plus antiparkinsonian drug therapy is significantly more effective than using only antiparkinsonian drug therapy. [1] Two groups were compared. In one group, Parkinson’s disease patients received only levodopa-benserazide as a means to alleviate symptoms. In the second group, levodopa-benserazide was combined with acupuncture therapy. The acupuncture plus...Weiterlesen

Abstract Acupuncture has been used in the therapy of Alzheimer disease (AD); however, its neural mechanisms are still unclear. The aim of this study is to examine the effect of acupuncture on the functional connectivity in AD by using resting-state functional magnetic resonance imaging (rs-fMRI). Twenty-eight subjects (14 AD and 14 normal controls) participated in this study. The rs-fMRI data were acquired before and after acupuncture stimulation at the acupoints of Tai chong (Liv3) and Hegu (LI4). During the baseline resting state, by using the amplitude of low-frequency fluctuations (ALFF), we found a significantly decreased or increased ALFF in the...Weiterlesen

Abstract OBJECTIVE: To preliminarily explore the effect of electroacupuncture (EA) on bladder and bowel dysfunction in patients with transverse myelitis. METHODS: Sixteen participants were treated with EA at bilateral BL32, BL33, and BL35 once a day, five times a week for the first 4 weeks, and once every other day, three times a week for the following 4 weeks. Patients were then followed up for 6 months. Bladder and bowel function, and the safety of EA, were assessed. RESULTS: After 8 weeks of treatment, five (5/16, 31%) patients resumed normal voiding, three (6/16, 38%) regained partially normal voiding, and five (5/16, 31%) had...Weiterlesen

Abstract OBJECTIVE: To observe the effects of acupuncture at different acupoints in yin meridians and yang meridians on lower limb muscle tension in children with spastic cerebral palsy. METHODS: Ninety children with spastic cerebral palsy aged between 2 to 6 years old were divided into a yin-meridian group, a yang-meridian group and a rehabilitation group, 30 cases in each one. The patients in the rehabilitation group were treated with routine rehabilitation treatment; the patients in the yin-meridian group were treated with routine rehabilitation treatment and acupuncture at Xuehai (SP 10), Yinlingquan (SP 9), Sanyinjiao (SP 6), Taixi (KI 3) and...Weiterlesen

Original Titel: A standardised frankincense extract reduces disease activity in relapsing-remitting multiple sclerosis (the SABA phase IIa trial) Weihrauch kennen die meisten als Räucherwerk aus der Kirche. In verschiedenen Religionen hat Weihrauch eine sehr lange Tradition, bereits die alten Ägypter verwendeten das getrocknete Harz des Weihrauchbaums. Weniger bekannt dürfte sein, dass Weihrauch früher auch als pflanzliches Heilmittel eingesetzt wurde. War es doch eine Zeit lang in Vergessenheit geraten, entdeckte ein Pharmakologe 1991 mögliche entzündungshemmende Eigenschaften von Weihrauch. Das passt dazu, dass es früher als entzündungshemmendes, schmerzlinderndes und antibakterielles pflanzliches Heilmittel galt. In Europa wurde es früher sogar bereits zur Behandlung...Weiterlesen

More evidence for the neural specificity of particular acupuncture points comes from a Chinese study that used fMRI to investigate the effects of acupuncture at Neiguan P-6. fMRI was performed on the brains of 36 healthy subjects while they received acupuncture at Neiguan P-6 and two control points (Daling P-7 and Guangming GB-37). Needling at Neiguan P-6 caused extensive signal decreases (deactivations) in cerebrocerebellar and subcortical areas, whereas needling at GB-37 induced widespread signal increases (activations). The deactivations persisted for a prolonged time following the end of needle stimulation. In addition, acupuncture at Neiguan P-6 (unlike stimulation at Daling P-7...Weiterlesen

von Petra Koczy Moxibustion zur Unterstützung der körperlichen Genesung nach Schlaganfall. Synergieeffekte durch Kombination von Reha-Training mit Moxa-Therapie: Die Wirksamkeit von Rehabilitationsmaßnahmen für Schlaganfallpatienten mit spastischer Hemiplegie konnte in einer chinesischen Studie durch zusätzliches Moxen gesteigert und dadurch den Patienten mehr Eigenständigkeit und Lebensqualität gegeben werden. Schlaganfall ist weltweit die dritthäufigste Todesursache. Aber selbst wenn es nicht zum Äußersten kommt, führt die zeitweilige Unterversorgung des Gehirns bei etwa 90 % der Patienten zu bleibenden Schädigungen. Diese können sich u.a. in kognitiven, psychischen oder sprachlichen Defiziten sowie Einschränkungen der motorischen Fähigkeiten äußern. Allein und in Kombination schränken sie die Lebensqualität der...Weiterlesen

Dimitrova Alexandra Medical Acupuncture. December 2017, Vol. 29, No. 6: 352-365 ABSTRACT Background: Peripheral neuropathy (PN) is defined as damage to the peripheral nervous system caused by a primary lesion or dysfunction. Multiple recent trials have suggested that acupuncture is beneficial for treating neuropathic pain. One challenge in acupuncture research is the lack of standardization of point selection, number of needles used, needle-retention time, needling depth, amount of needle manipulation, and use of moxibustion and electroacupuncture (EA). Objectives: This article presents a standardized acupuncture protocol for the treatment of PN that incorporates structural acupuncture principles based on proximity to peripheral...Weiterlesen

A Chinese herbal formula, ‘Ningdong granules’ (NDG), has been shown to reduce tics in children with Tourette’s syndrome. The formula, which contains the herbs Tian Ma (Rhizoma Gastrodiae), Dang Shen (Radix Codonopsis), Mai Men Dong (Radix Ophiopogonis) Bai Shao (Radix Paeoniae alba), Long Gu (Fossilia Ossis Mastodi), Mu Li (Concha Ostreae), Di Long (Pheretima) and Gan Cao (Radix Glycyrrhizae) has previously been used in China the treatment of children with attention deficit/hyperactivity disorder (ADHD) in China. In a randomised, double-blind study 120 paediatric Tourette’s patients were randomly divided into four groups. One group received NDG, another received usual drug treatment, consisting of the antipsychotic medicationhaloperidol (Hal), the third group...Weiterlesen

A Chinese herbal formula has shown potential for improving working memory performance in healthy adults, an Australian pilot study has found. Sailuotong (SLT) is a standardised three-herb formula that combines specific doses of the key bioactive constituents from the concentrated extracts of Panax ginseng (ginsenosides), Ginkgo biloba (flavone-glycosides) and Crocus sativus (crocins), which has been developed to enhance cognitive and cardiovascular function. Using a randomised crossover design, the study assessed the effect of treatment for one week with SLT and placebo on neurocognitive and cardiovascular function in 16 healthy adults. Neuropsychological testing showed that treatment with SLT, but not placebo,...Weiterlesen

A large, prospective cohort study carried out in Japanese seniors has found that consumption of green tea is significantly associated with a lower risk of developing functional disability (problems with daily activities, such as bathing or dressing). Information on daily green tea consumption and other lifestyle factors was collected via questionnaire from 13,988 Japanese individuals aged 65 or over, and subjects were followed up for three years. The results showed an inverse relationship between functional disability risk and the consumption of green tea – the more green tea people drank, the lower their disability risk. Nearly 13% of those who...Weiterlesen

ABSTRACT Objective: Motion sickness is the main cause of nausea-related symptoms during passive motion in transportation. The aim of this study was to evaluate the effects of electroacupuncture (EA) for the reduction of motion sickness symptoms. Materials and Methods: Study participants were randomly assigned into three groups: Group A, therapeutic EA; Group B, sham EA; and group C, a control group. After an EA session, participants were exposed to a motion stimulus, using a rotating chair. Their symptoms were measured using the Greek version of the Gianaros Motion Sickness Assessment Questionnaire (MSAQ). Application of verum EA and sham EA to the...Weiterlesen

ABSTRACT Background: Multiple sclerosis is considered a complex and heterogeneous disease. Approximately 85% of patients with multiple sclerosis indicate impaired gait as one of the major limitations in their daily life. Acupuncture studies found a reduction of spasticity and improvement of fatigue and imbalance in patients with multiple sclerosis, but there is a lack of studies regarding gait. Design: We designed a study of acupuncture treatment, according to the Heidelberg model of Traditional Chinese Medicine (TCM), to investigate if acupuncture can be a useful therapeutic strategy in patients with gait impairment in multiple sclerosis of relapsing-remitting type. The sample consisted...Weiterlesen

Abstract Objective To determine differences in cerebral activity evoked by acupuncture and conventional stroke treatment, and identify the treatment targets. Methods In total, 21 patients were randomly divided into two groups. Group A (11 patients) received both acupuncture and conventional treatment, while Group B (10 patients) received conventional treatment only. Resting-state functional magnetic resonance imaging (fMRI) was performed on each participant before and after treatment. Regional homogeneity (ReHo) analysis was performed to investigate the potential mechanism of acupuncture treatment by comparing differences in cerebral activity between treatments. Results Group A showed higher ReHo in the frontal lobe (BA6, BA46), supra-marginal...Weiterlesen

Objective: To observe clinical effects of acupuncture combined with blood-letting by a three-edged needle for treating Bell’s palsy of wind-heat syndrome at the acute stage. Methods: One hundred patients were randomly divided into a treatment group (50 cases) treated by acupuncture plus blood-letting and a control group (50 cases) treated by simple acupuncture. Four courses of treatments were given in both groups. The main symptoms and signs were observed and clinical effects evaluated with scores after one week, 2 weeks and one month of treatments respectively. Results: After treatment, the scores for symptoms and signs were significantly different from those...Weiterlesen

Original Titel: The Natural Product Curcumin as a Potential Coadjuvant in Alzheimer’s Treatment. Die Alzheimer-Erkrankung zeichnet sich durch eine zunehmende kognitive Beeinträchtigung der Patienten aus und betrifft rund 12 % der über 65-Jährigen. Die Weltgesundheitsorganisation WHO schätzt, dass über 48,6 Mio. Menschen weltweit an dieser Erkrankung leiden. Die Autoren dieser Studie haben in früheren Arbeiten eine Hypothese zu möglichen Mechanismen der Krankheitsentwicklung vorgeschlagen, die mit den klinischen Beobachtungen konsistent zu sein scheint. Nach diesem neuroimmunomodulatorischen Konzept löst das körpereigene Immunsystem eine Kaskade molekularer Signale aus, die letztlich zu Ansammlungen des fehlerhaft konstruierten Tau-Proteins in den Zellen, und damit zum Pfad der neuronalen...Weiterlesen

Simultaneous use of local acupoints together with points on the Governing vessel can promote functional repair after peripheral nerve injury, report Chinese investigators. The team compared the clinical efficacy of acupuncture at Governing vessel plus local channel points (GV/LC group) with acupuncture at local channel acupoints alone (LC group) in the treatment of 30 patients with peripheral nerve injury. In the GV/LC group, in addition to local channel points at the injury site, the following acupoints on the Governor vessel were stimulated: Baihui DU-20, Fengfu DU-16, Dazhui DU-14 and Shenzhu DU-12 (for injury of the upper limb), and Jizhong DU-6,...Weiterlesen

OBJECTIVE: To observe the clinical effects of acupuncture for diabetic peripheral neuropathy. METHODS: Totally 65 patients were randomly divided into a treatment group of 32 cases and a control group of 33 cases. On the basis of conventional treatment of diabetes, acupuncture was used in the treatment group, and inositol was orally administered in the control group. During a 3-month treatment, changes in the symptoms were observed. After basic treatment for both the two groups, acupuncture was used in the treatment group, and inositol was orally administered in the control group. The Basic Treatment All the patients were conventionally treated,...Weiterlesen

A PRISMA-compliant systematic review and meta-analysis Abstract: 1. Background Parkinson’s disease (PD) is the second-most-common chronic and progressive neurodegenerative disease. The long-term use of levodopa leads to a loss of efficacy and to complications. Therefore, many patients with PD have turned to complementary therapies to help relieve their symptoms. Acupuncture is most commonly used as a complementary therapy in patients with PD. This paper presents a systematic review and meta-analysis of the effects of acupuncture for patients with PD. This study was performed to summarize and evaluate evidence regarding the effectiveness of acupuncture in the relief of PD symptoms. 2....Weiterlesen

Original Titel: Chinese herbal medicine adjunct therapy in patients with acute relapse of multiple sclerosis: A systematic review and meta-analysis Viele Patienten mit Multipler Sklerose greifen zur Ergänzung ihrer Standardbehandlung auf alternative und komplementäre Medizin zurück. Die Studie von Song et al. (2017) untersuchte Effektivität und Sicherheit von chinesischer Kräutermedizin als Ergänzung zur Standardtherapie bei Patienten mit akuten Schüben der Multiplen Sklerose. Es konnten die Ergebnisse von 20 Studien mit 1.100 Patienten ausgewertet werden. Die 5 am häufigsten gebrauchten Gewürze waren die Chinesische Engelwurz, die Uralsüßholzwurzel, die Rote Pfingstrosenwurzel, die Rehmannia–Wurzelknolle und Seidenraupenlarven. Die Auswertung der Ergebnisse zeigte, dass die...Weiterlesen

Zur Unterstützung der konventionellen Medikation erzielt Akupunktur eine höhere Effektivität in der Linderung der Beschwerden als diese allein und kann somit die Lebensqualität von Parkinson-Patienten deutlich erhöhen. Laut der Angaben der Deutschen Parkinson-Gesellschaft sind weltweit rund 4,1 Mill. Menschen, also knapp zwei Prozent der Weltbevölkerung im Alter von über 60 Jahren an Morbus Parkinson, der zweithäufigsten neurodegenerativen Erkrankung nach Morbus Alzheimer, erkrankt. Zwischen 250.000 und 280.000 Betroffene mit dieser Erkrankung sind in Deutschland verzeichnet. [1] Die  früher auch als „Schüttellähmung“ bezeichnete Erkrankung ist durch einen Mangel an dem Nervenbotenstoff Dopamin gekennzeichnet, der durch das kontinuierliche Absterben von speziellen Nervenzellen verursacht...Weiterlesen

Eine echte Akupunktur verändert bei Patienten mit Karpaltunnelsyndrom die Verarbeitung von Nervenimpulsen im somatosensorischen Cortex des Gehirns. Dies zeigen die Ergebnisse einer Studie in Brain (2017; doi: 10.1093/brain/awx015). Die Forscher untersuchten 80 Patenten im Durchschnittsalter von 49 Jahren mit Karpaltunnelsyndrom. Sie wurden in drei Gruppen aufgeteilt: Die erste erhielt eine Elektro-Akupunktur an der betroffenen Hand, die zweite eine Elektro-Akupunktur an Knöchel und Ferse des gegenüberliegenden Beines und die dritte eine Schein-Elektroakupunktur an der betroffenen Hand – mit Nadeln, die nur in die Haut drückten und nicht stachen und keinen elektrischen Impuls übertrugen. Die Therapie dauert acht Wochen, in denen es...Weiterlesen

von Rainer Lüdtke, Quelle: www.carstens-stiftung.de Der Schlaganfall ist die dritthäufigste Todesursache in Deutschland. Mittlerweile gibt es eine erkleckliche Anzahl wissenschaftlicher Untersuchungen zu der Frage, ob die Akupunktur auch bei der Behandlung des Schlaganfalls sinnvoll ist. Unter einem Schlaganfall versteht man eine schlagartig einsetzende schwere Funktionsstörung des Gehirns, weil die Blutversorgung bestimmter Gehirnbezirke deutlich vermindert oder vollständig unterbrochen wird, entweder durch Blutungen oder durch Gefäßverschlüsse. Der Schlaganfall ist nach den koronaren Herzkrankheiten und bösartigen Tumorerkrankungen die dritthäufigste Todesursache in Deutschland. Man schätzt, dass jedes Jahr fast eine Millionen Bundesbürger einen Schlaganfall erleiden. Mehr als zwei Drittel davon sterben (meist sehr früh)...Weiterlesen

Adding acupuncture to a low dose of gabapentin is clinically useful for controlling the symptoms of restless legs syndrome (RLS), and has an additive therapeutic effect over gabapentin alone. Iranian investigators randomly allocated 46 RLS patients to receive either ten sessions of acupuncture (at bilateral Shenshu BL-23, Ganshu BL-18, Chengjin BL-56, Chenshan BL-57, Jinggu BL-64, Zusanli ST-36, Liangqiu ST-34, Shangqiu SP-5, Xuehai SP-10, Shanyijiao SP-6, Taixi KID-3, Yanglingquan GB-34 and Xuanzhong GB-39) plus gabapentin, or gabapentin alone over four weeks. Although both groups of patients showed significant improvements in symptom scores at the end of the treatment period and at...Weiterlesen

Adding acupuncture to routine care can improve cognitive status and daily living of patients with vascular dementia (VaD). A total of 68 patients received either acupuncture or usual care alone. The main acupoints used were: Baihui DU-20, Sishencong M-HN1, Shenting DU-24, Shanzhong REN-17, Neiguan P-6, Zhongwan REN-12, Qihai REN-6, Xuehai SP-10 and Zusanli ST-36, with Fengchi GB-20, Fenglong ST-40, Taichong LIV-3, Sanyinjiao SP-6 and Tianshu ST-25 included as auxiliary acupoints. Acupuncture point prescriptions were individualised to each patient at the discretion of the acupuncturist. Patients received up to 21 acupuncture sessions during a period of six weeks plus routine care....Weiterlesen

Quelle (15 MARCH 2018): http://www.healthcmi.com Researchers find acupuncture highly effective and that scalp acupuncture is particularly important for post-stroke patients. Scalp acupuncture significantly boosts the effectiveness of body style acupuncture for the treatment of post-stroke facial paralysis. In a randomized controlled trial, researchers determined that the addition of scalp acupuncture to a standard acupuncture therapeutic regimen increases positive patient outcomes by over 20%. In the investigation, body style acupuncture achieved a 71.4% total effective rate. The addition of scalp acupuncture to the treatment protocol increased the total effective rate to 93.1%. [1] Based on the data, the researchers conclude that...Weiterlesen

Acupuncture can reduce pain and medication use in patients with idiopathic trigeminal neuralgia (ITN). In a longitudinal case-control study, Brazilian researchers compared 30 healthy subjects with 60 ITN patients, who were randomly assigned to receive acupuncture, sham acupuncture or drug treatment (carbamazepine). Patients in the acupuncture group underwent 10 weekly sessions of verum acupuncture. Needles were applied at Hegu 4 L.I.-4, Sanjian L.I.-3 and Neiting ST-44 for all patients, plus other points according to the trigeminal nerve branch affected in each individual (ophthalmic branch – Cuanzhu BL-2, Yangbai GB-14 and Yuyao M-HN-6; maxillary branch – Sibai ST-2, Juliao ST-3 and...Weiterlesen

Acupuncture results in both clinical and morphological improvement of the median nerve at the wrist in patients with carpal tunnel syndrome (CTS) according to researchers from Turkey. Forty-five limbs of 27 female patients were randomly divided into acupuncture and control groups. All patients used a night wrist splint, and patients in the acupuncture group received additional needling at nine acupuncture points (Daling P-7, Ximen P-4, Neiguan P-6, Laogong P-8, Qingling HE-2, Shenmen HE-7, Shaofu HE-8, Taiyuan LU-9 and Quchi L.I.-11). Acupuncture treatment was applied two or three times a week for four weeks (a total of 10 sessions). While symptom...Weiterlesen

Quelle (12 MARCH 2018): http://www.healthcmi.com Acupuncture restores normal swallowing in post-stroke patients and investigators document an optimal approach to patient care. Researchers find low frequency electroacupuncture more effective than high frequency electroacupuncture for the relief of post-stroke dysphagia (difficulty or discomfort in swallowing). Guangzhou University of Traditional Chinese Medicine researchers combined acupuncture with general health care and rehabilitation exercises into an integrated treatment protocol. [1] They conclude that acupuncture is effective for the treatment of post-stroke dysphagia and that patients receiving low frequency electroacupuncture had superior patient outcomes compared with patients receiving high frequency electroacupuncture. The total effective rate in...Weiterlesen

Acupuncture treatment can improve walking gait in patients with multiple sclerosis, report Portuguese investigators. Gait impairment was evaluated using the 25-foot walk test in 20 individuals with relapsing-remitting multiple sclerosis, who were then randomised to either verum or sham acupuncture. Verum acupuncture was administered at Liangqiu ST-34 Weizhong BL-40 and Chengshan BL-57, while sham acupuncture consisted of needling at non-acupuncture points located two cun laterally to the verum points. Verum acupuncture led to a significant decrease in time taken to walk 25 feet. By contrast, differences in time to walk 25 feet were not statistically significant for sham acupuncture. Following...Weiterlesen

A pilot cohort study from Taiwan has demonstrated that acupuncture has a clinically significant and immediate effect on reducing dizziness and vertigo among hospital emergency department (ED) patients. A total of 60 participants who presented to the ED complaining of dizziness and vertigo, and for whom serious causes had been ruled out, were randomised to treatment and control groups. The treatment group received one 30-minute session of acupuncture at Zusanli ST-36 and Neiguan P-6. The control group underwent a sham procedure – acupressure seeds placed without stimulation at non-acupoints one centimetre from the real acupoints used in the study. Compared...Weiterlesen

Quelle (17 MARCH 2014): http://www.healthcmi.com A new report tracks the success of acupuncture for the treatment of schizophrenia. This chronic mental disorder is characterized by mental fragmentation, illogic, disconnected emotional responses, delusions and a breakdown of the line between fantasy and reality. Researchers documented a case study wherein acupuncture improved daily functions, sleep and reduced pain, depression and mental disturbances due to hallucinations. This latest research is bolstered by additional research finding that acupuncture alleviates both schizophrenia and the side effects of psychiatric medication. Taking a look a this most recent research, a 63 year old woman suffered from chronic hallucinations...Weiterlesen

Clinical Research Wang Yan-jun (王艳君)a, , Han Yi-xu (韩一栩)b, Hu Yu-tong (胡雨桐)a Abstract Objective To observe the comprehensive curative effect of acupuncture manipulation of regulating governor vessel and unblocking brain for post stroke depression associated with anxiety. Methods Sixty-four patients with post stroke depression associated with anxiety were randomly divided into 2 groups according to the random numbers generated by spss16.0 software, the group of acupuncture manipulation of regulating governor vessel and unblocking brain (group A) and medication group (group B), with 32 patients in each group. Acupuncture manipulation of regulating governor vessel and unblocking brain was performed in group...Weiterlesen

Abstract Background: Alzheimer’s disease (AD) is the most common cause of dementia. However, none of medical treatment can stop or reverse the underlying neurodegenerative of AD at present. Acupuncture has attracted more and more attention in recent years due to its efficacy and very few side effects. Lately, a systematic review has thought that the evidence on the effectiveness of acupuncture in improving the cognitive function of AD patients was not powerful enough. Therefore, the aim of this study is to explore the efficacy and safety of acupuncture in patients with mild to moderate AD. Methods: This was a randomized,...Weiterlesen

24 February 2017 Acupuncture benefits memory, learning, and the brain in an Alzheimer’s disease study. In a controlled experiment, researchers discovered two important clinical benefits provided by stimulation of scalp acupuncture points; acupuncture improves spatial learning and memory. Additionally, the researchers discovered that acupuncture improves brain glucose metabolism. Let’s take a look at the results. Researchers at the Beijing University of Chinese Medicine demonstrate that electroacupuncture improves spatial memory and learning in mice with Alzheimer’s disease (AD). [1] To test electroacupuncture’s effectiveness for the treatment of Alzheimer’s disease and its related upregulation of glucose metabolism in the hippocampus, the researchers...Weiterlesen

14 March 2018 Researchers find acupuncture effective for the treatment of Bell’s Palsy—a type of facial paralysis. In one independent investigation, electroacupuncture produced optimal results. In another investigation, warm needle acupuncture combined with vitamin and drug injections produced excellent results. Let’s take a look at the results after a brief introduction. In an online acupuncture continuing education course at HealthCMi it is noted, “Bell’s Palsy is an acute facial paralysis caused by inflammation of the seventh cranial nerve (facial nerve). … A key feature of Bell’s Palsy is its sudden onset. Bell’s Palsy also causes unilateral impairment of motor function....Weiterlesen

Using fMRI, Chinese researchers have shown that the organisation of functional brain networks is altered after acupuncture and that these alterations exhibit point specificity. Eighteen healthy young adults were scanned before and after acupuncture at Zusanli ST-36 and a sham point. They found that, while functional brain networks showed increased local efficiency after acupuncture, there were no significant differences after sham, indicating that true acupuncture at Zusanli ST-36 was capable of coordinating local information flow over the whole brain. True acupuncture at Zusanli ST-36 also reliably elicited effects in various specific brain regions (including the left hippocampus, anterior cingulate cortex,...Weiterlesen

Quelle (24 JULY 2015): http://www.healthcmi.com Researchers find acupuncture effective for alleviating chemotherapy induced peripheral neuropathy (CIPN) for patients with colon cancer. Neurotoxicity from chemotherapy may damage nerve fibers and lead to symptoms including pain, burning sensations, tingling, muscle weakness, balance disorders, paresthesia, dysesthesia, cold or heat sensitivity in the hands and feet, and a “glove and stocking” distribution of symptoms. The paresthesia is often experienced as a bilateral pins and needles sensation. Severity ranges from mild to debilitating. The researchers summarize their findings into three main benefits of acupuncture for patients with CIPN: Acupuncture administered prior to chemotherapy prevents CIPN. Use...Weiterlesen

The clinical efficacy of  ‘5-Ling Granule’ (5-LGr), a proprietary herbal formula, is comparable to that of the drug tiapride (a selective dopamine D2-receptor antagonist) for reducing tics in children with Tourette’s syndrome. In a multi-centre trial, Chinese investigators randomised 603 patients with TS to treatment with placebo, tiapride or 5-LGr for eight weeks. While all patients experienced a reduction in tics over time, 5-LGr and tiapride produced significantly greater improvements compared with placebo. 74% of patients in the 5-LGr arm and 68.3% in the tiapride arm showed a clinical response to treatment. These response rates were significantly higher than placebo...Weiterlesen